Desmoplastic Fibroma of Bone
Desmoplastic fibroma of bone is an intraosseous, locally aggressive neoplasm, constituted by spindle cells and abundant collagen production. Beta-catenin is usually positive in the cytoplasm of neoplastic cells. It corresponds to less than 0.1 % of primary bone neoplasms. Its main incidence is in the second and third decade of life. Males correspond to more than 70 % of the cases. Most cases occur in the jaw; metaphysis of long bones, especially the distal end of the radius; scapula; and pelvis. Radiographs show a lytic, well-defined lesion, with no peripheral sclerosis or periosteal reaction. Soft tissue expansion of the lesion may occur. Wide en bloc resection is the treatment of choice.