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General Aspects of Adverse Cutaneous Drug Reactions

  • Esen Özkaya
  • Kurtuluş Didem Yazganoğlu
Chapter

Abstract

Adverse cutaneous drug reactions (ACDR) or drug eruptions represent one of the most common types of adverse reactions to drug therapy. The overall incidence rate is estimated around 2–3 % in hospitalized patients. Antibiotics, nonsteroidal antiinflammatory drugs (NSAIDs), and anticonvulsants are usually regarded as the most common inducers, but almost every drug may cause skin reactions. Advanced age, polypharmacy, and female gender are among the main factors predisposing to ACDR.

Keywords

Drug eruption Cardiovascular drugs Maculopapular Erythema multiforme Acute generalized exanthematous pustulosis Photosensitivity Hyperpigmentation Vasculitis Angioedema Erythroderma Stevens–Johnson syndrome Toxic epidermal necrolysis Drug rash with eosinophilia and systemic symptoms 

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Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  • Esen Özkaya
    • 1
  • Kurtuluş Didem Yazganoğlu
    • 1
  1. 1.Department of Dermatology and VenereologyIstanbul University Istanbul Medical FacultyIstanbulTurkey

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