Uncommon Dementias

  • Camilla FerrariEmail author
  • Benedetta Nacmias
  • Sandro Sorbi


Dementia is becoming a worldwide phenomenon. Alzheimer’s disease represents the first cause of cognitive impairment, followed by vascular and frontotemporal dementia. However, in addition to these well-studied causes, there is a large number of conditions that can cause dementia, such as infections, toxic–metabolic conditions, inflammatory–autoimmune disorders, or metabolic inborn errors. These uncommon causes of dementia, due to their heterogeneous clinical presentation, lack diagnostic criteria and occur rarely, are often misdiagnosed. Prevalence has been only partially estimated in young patients (age at onset <65 years), and management is based only on a few expert suggestions. However, correct diagnosis is of great importance, since some of these dementias are treatable and reversible.

This chapter presents a comprehensive summary of etiologies, clinical presentation, typical features, diagnostic strategies, and treatments of known, uncommon dementias.


Uncommon dementia Young-onset dementia Neurodegenerative disease Reversible dementia 


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Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  • Camilla Ferrari
    • 1
    Email author
  • Benedetta Nacmias
    • 1
  • Sandro Sorbi
    • 1
  1. 1.Department of Neuroscience, Psychology, Drug Research and Child Health (NEUROFARBA)University of FlorenceFlorenceItaly

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