Abstract
Cigarette smoking delays wound healing and is associated with higher complication rates after reconstructive and aesthetic procedures including microsurgery and free tissue transfer, arterial reconstruction, subcutaneous mastectomy, breast reconstruction, and facelift surgery. One mechanism shown to prolong flap survival in many clinical situations and animal models is sympathectomy, which is one of the proposed components of the delay phenomenon. The purpose of study presented in this chapter is assessment whether sympathectomy has the potential to improve the survival of muscle flaps during acute cigarette smoking. We used the rat cremaster muscle flap model, which allowed us to examine the acute effect of cigarette smoking on the microcirculation of both innervated and denervated axial muscle flaps, including changes in hemodynamics and leukocyte behavior. The important finding in this study was the significant difference in vessel behavior during and after smoking when comparing the innervated and denervated groups.
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Dydymski, T., Siemionow, M.Z. (2015). Microcirculation and Smoking. In: Siemionow, M. (eds) Plastic and Reconstructive Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-6335-0_13
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DOI: https://doi.org/10.1007/978-1-4471-6335-0_13
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