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Developing Insights in Cartilage Repair pp 269–293Cite as

Cartilage Repair, Replacement, and Regenerative Strategies for Osteochondral Lesions of the Talus

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Abstract

Osteochondral lesions of the talus present a formidable treatment challenge to the orthopaedic surgeon. Historical cartilage repair strategies often result in the formation of fibrocartilage leading to suboptimal clinical results. With advances in regenerative medicine, modern surgical techniques are diverse and employ autograft, allograft, and tissue-engineered constructs for cartilage repair. Fresh and particulated juvenile allograft transplantation have become popular options in the United States. Wordwide, both cellular and acellular tissue-engineered constructs are utilized. In all cases, there is still debate as to the optimal cell source and scaffold material and only short-term clinical results are available. This chapter will review these current as well as experimental techniques for cartilage repair of osteochondral lesions of the talus.

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, Duke University Medical Center, 4709 Creekstone Drive, Suite 200, Durham, NC, 27703, USA

    Samuel B. Adams MD

  2. Department of Orthopaedic Surgery, Duke University Medical Center, North Carolina Orthopaedic Clinic, 3609 Southwest Durham Drive, Durham, NC, 27707, USA

    Selene G. Parekh MD, MBA & Lew C. Schon MD

  3. Department of Orthopaedic Surgery, Clinica Alemana, 5951 Vitacura Avenue, Santiago, Chile

    Diego H. Zanolli de Solminihac MD

  4. Joint Implant Surgeons of Florida, 7331 College Parkway, Suite 300, Fort Myers, FL, 33907, USA

    Evgeny E. Krynetskiy MD

  5. Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA

    Mark E. Easley MD

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  1. Samuel B. Adams MD
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Correspondence to Samuel B. Adams MD .

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Editors and Affiliations

  1. Department of Orthopaedic Surgery, Maastricht University Medical Center, Maastricht, The Netherlands

    Pieter J. Emans

  2. Department of Orthopedics, University of Gothenburg, Gothenburg, Sweden

    Lars Peterson

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Adams, S.B., Parekh, S.G., de Solminihac, D.H.Z., Krynetskiy, E.E., Schon, L.C., Easley, M.E. (2014). Cartilage Repair, Replacement, and Regenerative Strategies for Osteochondral Lesions of the Talus. In: Emans, P., Peterson, L. (eds) Developing Insights in Cartilage Repair. Springer, London. https://doi.org/10.1007/978-1-4471-5385-6_16

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  • Published:

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-5384-9

  • Online ISBN: 978-1-4471-5385-6

  • eBook Packages: MedicineMedicine (R0)

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