Advertisement

The Use of Lasers and Light Treatment for Hair Growth and Hair Transplantation

  • Nicole E. RogersEmail author
Chapter

Abstract

Laser light presents a non-invasive treatment option for patients with hair loss. In this chapter, we examine data for the use of ultraviolet, fractionated, and low-level light therapy (LLLT) for the treatment of male and female pattern hair loss, as well as alopecia areata and cicatricial alopecias. Mechanisms for laser-induced hair growth include localized vasodilation and skin wounding. More data about ideal dosing and treatment parameters is still needed.

Keywords

Hair loss Hair growth Low-Level Light Therapy (Lllt) Minoxidil Finasteride Laser Hypertrichosis Alopecia 

References

  1. 1.
    Mester E, Szende B, Gartnerne TJ. Influence of laser beams on the growth of hair in mice. Kiserl Orvostud. 1967;19:628–31.Google Scholar
  2. 2.
    Desai S, Mahmoud BH, Bhatia AC, Hamzavi IH. Paradoxical hypertrichosis after laser therapy: a review. Dermatol Surg. 2010;36:291–8.PubMedCrossRefGoogle Scholar
  3. 3.
    Alajlan A, Shapiro J, Rivers JK, MacDonald N, Wiggin J, Lui H. Paradoxical hypertrichosis after laser epilation. J Am Acad Dermatol. 2005;53:85–8.PubMedCrossRefGoogle Scholar
  4. 4.
    Bernstein EF. Hair growth induced by diode laser treatment. Dermatol Surg. 2005;31:584–6.PubMedCrossRefGoogle Scholar
  5. 5.
    Moreno-Arias G, Castelo-Branco C, Ferrando J. Paradoxical effect after IPL photoepilation. Dermatol Surg. 2002;28:1013–6.PubMedGoogle Scholar
  6. 6.
    Moreno-Arias G, Castelo-Branco C, Ferrando J. Side-effects after IPL photoepilation. Dermatol Surg. 2002;28:1131–4.PubMedGoogle Scholar
  7. 7.
    Radmanesh M. Paradoxical hypertrichosis and terminal hair change after intense pulsed light hair removal therapy. J Dermatolog Treat. 2009;20:52–4.PubMedCrossRefGoogle Scholar
  8. 8.
    Willey A, Torrontegui J, Azpiazu J, et al. Hair stimulation following laser and intense pulsed light photo-epilation: review of 543 cases and ways to manage it. Lasers Surg Med. 2007;39:297–301.PubMedCrossRefGoogle Scholar
  9. 9.
    Kontoes P, Vlachos S, Konstantinos M, et al. Hair induction after laser-assisted hair removal and its treatment. J Am Acad Dermatol. 2006;54:64–7.PubMedCrossRefGoogle Scholar
  10. 10.
    Ehrreich SJ, Furchgott RF. Relaxation of mammalian smooth muscles by visible and ultraviolet radiation. Nature. 1968;218:682–4.PubMedCrossRefGoogle Scholar
  11. 11.
    Furchgott RF, Jothianandan D. Endothelium-dependent and –independent vasodilation involving cyclic GMP: relaxation induced by nitric oxide, carbon monoxide, and light. Blood Vessels. 1991;28:52–61.PubMedGoogle Scholar
  12. 12.
    Kligman AM, Strauss JS. The formation of vellus hair follicles from human adult epidermis. J Invest Dermatol. 1956;27:19–23.PubMedCrossRefGoogle Scholar
  13. 13.
    Ito M, Yang Z, Andl T, Cui C, Kim N, Millar S, Cotsarelis G. Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding. Nature. 2007;447:316–20.PubMedCrossRefGoogle Scholar
  14. 14.
    Beachkofsky TM, Henning JS, Hivnor CM. Induction of de novo hair regeneration in scars after fractionated carbon dioxide laser therapy in three patients. Dermatol Surg. 2011;37:1365–8.PubMedCrossRefGoogle Scholar
  15. 15.
    McGuff PE, Buchnell D, Soroff S, Deterling RA. Studies of the surgical applications of laser (light amplification by stimulated emission of radiation). Surg Forum. 1963;14:143–5.PubMedGoogle Scholar
  16. 16.
    Leavitt M, Charles G, Heyman E, Michael D. HairMax LaserComb laser phototherapy device in the treatment of male androgenetic alopecia: a randomized, double-blind, sham device-controlled, multicentre trial. Clin Drug Investig. 2009;29:283–92.PubMedCrossRefGoogle Scholar
  17. 17.
    Kim H, Choi JW, Kim JY, Shin JW, Lee SJ, Huh CH. Low-level light therapy for androgenetic alopecia: a 24-week, randomized, double-blind, sham-device-controlled multicenter trial. Dermatol Surg. 2013;39:1177–83.PubMedCrossRefGoogle Scholar
  18. 18.
    Avram MR, Rogers NE. The use of low-level light for hair growth: part I. J Cosmet Laser Ther. 2009;11:110–7.PubMedCrossRefGoogle Scholar
  19. 19.
    Lee GY, Lee SJ, Kim WS. The effect of a 1550 nm fractional erbium-glass laser in female pattern hair loss. J Eur Acad Dermatol Venereol. 2011;25:1450–4.PubMedCrossRefGoogle Scholar
  20. 20.
    Healy E, Rogers S. PUVA treatment for alopecia areata- does it work? A retrospective review of 102 cases. Br J Dermatol. 1993;129:42–4.PubMedCrossRefGoogle Scholar
  21. 21.
    Taylor CR, Hawk JL. PUVA treatment of alopecia areata partialis, totalis, and universalis: audit of 10 years’ experience at St. John’s Institute of Dermatology. Br J Dermatol. 1995;133:914–8.PubMedCrossRefGoogle Scholar
  22. 22.
    Yoo KH, Kim MN, Kim BJ, Kim CW. Treatment of alopecia areata with fractional photothermolysis laser. Int J Dermatol. 2010;49:842–8.Google Scholar
  23. 23.
    Cho S, Choi MJ, Zheng Z, Goo B, Kim DY, Cho SB. Clinical effects of non-ablative and ablative fractional lasers on various hair disorders: a case series of 17 patients. J Cosmet Laser Ther. 2013;15:74–7.PubMedCrossRefGoogle Scholar
  24. 24.
    Al-Mutairi N. 308-nm excimer laser for the treatment of alopecia areata in children. Pediatr Dermatol. 2009;26:547–50.PubMedCrossRefGoogle Scholar
  25. 25.
    Al-Mutairi N. 308-nm excimer laser for the treatment of alopecia areata. Dermatol Surg. 2007;33:1483–7.PubMedCrossRefGoogle Scholar
  26. 26.
    Gundogan C, Greve B, Raulin C. Treatment of alopecia areata with the 308-nm xenon chloride excimer laser: case report of two successful treatments with excimer laser. Lasers Surg Med. 2004;34:86–90.PubMedCrossRefGoogle Scholar
  27. 27.
    Waiz M, Saleh AZ, Hayani R, Jubory SO. Use of the pulsed infrared diode laser (904 nm) in the treatment of alopecia areata. J Cosmet Laser Ther. 2006;8:27–30.PubMedCrossRefGoogle Scholar
  28. 28.
    Wikramanayake TC, Rodriguez R, Choudhary S, Mauro LM, Nouri K, Schachner LA, Jimenez JJ. Effects of the Lexington LaserComb on hair regrowth in the C3H/HeJ mouse model of alopecia areata. Lasers Med Sci. 2012;27:431–6.PubMedCrossRefGoogle Scholar
  29. 29.
    King LE, Silva KA, Kennedy VE, Sundberg JP. Lack of response to laser comb in spontaneous and graft-induced alopecia areata in C3H/HeJ mice. J Invest Dermatol. 2014;134:264–6.PubMedCrossRefGoogle Scholar
  30. 30.
    Wikramanayake TC, Villasante AC, Mauro LM, Nouri K, Schachner LA, Perez CI, Jimenez JJ. Low-level laser treatment accelerated hair regrowth in a rat model of chemotherapy-induced alopecia. Lasers Med Sci. 2013;28:701–6.PubMedCrossRefGoogle Scholar
  31. 31.
    Duvic M, Lemak NA, Valero V, Hymes SR, Farmer KL, Hortobagyi GN, et al. A randomized trial of minoxidil in chemotherapy-induced alopecia. J Am Acad Dermatol. 1996;35:74–8.PubMedCrossRefGoogle Scholar
  32. 32.
    Navarini AA, Kolios AG, Prinz-Vavricka BM, Haug S, Trueb RM. Low-dose excimer 308-nm laser for treatment of lichen planopilaris. Arch Dermatol. 2011;147:1325–6.PubMedCrossRefGoogle Scholar
  33. 33.
    Neidel FG, Fuchs M, Krahl D. Laser-assisted autologous hair transplantation with the Er:YAG laser. J Cutan Laser Ther. 1999;1:229–31.PubMedCrossRefGoogle Scholar
  34. 34.
    Avram MR. Laser-assisted hair transplantation – a status report in the 21st centrury. J Cosmet Dermatol. 2005;4:135–9.PubMedCrossRefGoogle Scholar
  35. 35.
    Unger WP, David LM. Laser hair transplantation. J Dermatol Surg Oncol. 1994;20:515–21.PubMedCrossRefGoogle Scholar
  36. 36.
    Villnow MM, Feriduni B. Update on laser-assisted hair transplantation. Dermatol Surg. 1998;24:749–54.PubMedGoogle Scholar
  37. 37.
    Gupta A, Dai T, Hamblin MR. Effect of red and near-infrared wavelengths on low-level laser (light) therapy-induced healing of partial-thickness dermal abrasion in mice. Lasers Med Sci. 2014;29:257–65.PubMedCrossRefGoogle Scholar
  38. 38.
    Avram MR, Leonard Jr RT, Epstein ES, William JL, et al. The current role of laser/light sources in the treatment of male and female pattern hair loss. J Cosmet Laser Ther. 2007;9:27–8.PubMedCrossRefGoogle Scholar
  39. 39.
    Rajput RJ. Controversy: is there a role for adjuvants in the treatment of male pattern hair loss? J Cutan Aesthet Surg. 2010;3:82–6.PubMedCentralPubMedGoogle Scholar

Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  1. 1.Department of DermatologyTulane University School of MedicineMetairieUSA

Personalised recommendations