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Basic Principles of Lasers: Interactions Between Lasers and Tissue

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Lasers have become extremely important treatment devices in the field of dermatology. They have a variety of applications, ranging from the treatment of vitiligo, cutaneous T-cell lymphoma, hair removal, and skin resurfacing, among others. It is therefore fundamental for the clinician to have an understanding of laser-tissue interactions.


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  1. Carroll L, Humphreys TR. LASER-tissue interactions. Clin Dermatol. 2006;24(1):2–7.

    Article  PubMed  Google Scholar 

  2. Herd RM, Dover JS, Arndt KA. Basic laser principles. Dermatol Clin. 1997;15(3):355–72.

    Article  CAS  PubMed  Google Scholar 

  3. Tanzi EL, Lupton JR, Alster TS. Lasers in dermatology: four decades of progress. J Am Acad Dermatol. 2003;49:1–31.

    Article  PubMed  Google Scholar 

  4. Anderson RR, Parrish JA. The optics of human skin. J Invest Dermatol. 1981;77:13–9.

    Article  CAS  PubMed  Google Scholar 

  5. Anderson RR, Parrish JA. Selective photothermolysis: precise micro- surgery by selective absorption of pulsed radiation. Science. 1983;220:524–7.

    Article  CAS  PubMed  Google Scholar 

  6. Reinisch L. Laser physics and tissue interactions. Otolaryngol Clin North Am. 1996;29:893–914.

    CAS  PubMed  Google Scholar 

  7. Massey R, Marrero G, Goel-Bansal M, et al. Lasers in dermatology: a review. Lasers Dermatol. 2001;67:477–84.

    CAS  Google Scholar 

  8. Ries W, Speweye M. Cutaneous applications of lasers. Otolaryngol Clin North Am. 1996;29:915–29.

    CAS  PubMed  Google Scholar 

  9. Sakamoto FH, Avram MM, Anderson RR. Lasers and other energy technologies – principles & skin interactions. In: Bolognia J, editor. Dermatology. 3rd ed. London: Elsevier; 2013. p. 2251–4.

    Google Scholar 

  10. Anderson RR, Margolis RJ, Watenabe S, et al. Selective photo- thermolysis of cutaneous pigmentation by Q-switched Nd:YAG laser pulses at 1064, 532, and 355 nm. J Invest Dermatol. 1989;93:28–32.

    Article  CAS  PubMed  Google Scholar 

  11. Ara G, Anderson RR, Mandel KG, et al. Irradiation of pigmented melanoma cells with high intensity pulsed radiation generates acoustic waves and kills cells. Lasers Surg Med. 1990;10:52–9.

    Article  CAS  PubMed  Google Scholar 

  12. Polla LL, Margolis RJ, Dover JS, et al. Melanosomes are a primary target of Q-switched ruby laser irradiation in guinea pig skin. J Invest Dermatol. 1987;89:281–6.

    Article  CAS  PubMed  Google Scholar 

  13. Taylor CR, Anderson RR, Gange RW, et al. Light and electron microscopic analysis of tattoos treated by Q-switched ruby laser. J Invest Dermatol. 1991;97:131–6.

    Article  CAS  PubMed  Google Scholar 

  14. Anderson RR. Lasers in dermatology: a critical update. J Dermatol. 2000;27:700–5.

    CAS  PubMed  Google Scholar 

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Correspondence to Omar A. Ibrahimi MD, PhD .

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© 2014 Springer-Verlag London

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Pothiawala, S., Kilmer, S.L., Ibrahimi, O.A. (2014). Basic Principles of Lasers: Interactions Between Lasers and Tissue. In: Nouri, K. (eds) Handbook of Lasers in Dermatology. Springer, London.

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-5321-4

  • Online ISBN: 978-1-4471-5322-1

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