Abstract
Aims– The objective of this study was to identify clinical, electrocardiographic, and echocardiographic characteristics of atrial flutter catheter ablation in patients with aneurismal dilated atrium using EnSite System noncontact mapping.
We perform reconstruction of the cavotricuspid isthmus in order to verify if the isthmus anatomy correlated with the isthmus ablation outcome. We tried to locate the sites of conduction gaps and to verify if sites of conduction gaps resistant to ablation correlated with specific anatomical particularities.
Methods and Results – Isthmus was arbitrarily divided in an anterior—close to the tricuspid annulus—central, and inferior—close to the inferior vena cava orifice—portion.
A gap of the resumed conduction through the IVC-TA isthmus was delineated as a mechanism of recurrence and ablated with one and three radio-frequency applications. In 45 of the 79 patients a total of 52 gaps were found. Seventy-three percent of gaps were in the central portion of the isthmus, 8 % was in an anterior portion close to the tricuspid annulus, and 19 % were in an inferior portion near the edge of the inferior vena cava orifice. No specific anatomical structures were identified as being correlated with these sites. In the 16 patients with a total of 18 gaps, all these gaps were located at the same site: the border between the central and inferior portion of the isthmus at the level of a prominent Eustachian ridge.
Conclusion At patients with right aneurismal atrium the isthmus presents anatomical variants which may represent a site of conduction gaps “resistant” to ablation.
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References
Olshansky B, Okumura K, Hess PG, Waldo AL. Demonstration of an area of slow conduction in human atrial flutter. J Am Coll Cardiol. 1990;16:1639–48.
Cabrera JA, Sanchez-quintana D, Farre J, Rubio JM, Ho SY. The inferior right atrial isthmus: further architectural insights for current and coming ablation technologies. J Cardiovasc Electrophysiol. 2005;16(4):402–8.
Waki K, Saito T, Becker AE. Right atrial flutter isthmus revisited: normal anatomy favors nonuniform anisotropic conduction. J Cardiovasc Electrophysiol. 2000;11:90–4.
Saremi F, Pourzand L, Krishnan S, Ashikyan O, Gurudevan SV, Narula J, Kaushal K, et al. Right atrial cavotricuspid isthmus: anatomic characterization with multi-detector row CT. Radiology. 2008;247:658–68.
Lim KT, Murray C, Liu H, Weerasooriya R. Preablation magnetic resonance imaging of the cavotricuspid isthmus. Europace. 2007;9:149–53.
Scaglione M, Caponi D, Di Donna P, Riccardi R, Bocchiardo M, Azzaro G, Leuzzi S, et al. Typical atrial flutter ablation outcome: correlation with isthmus anatomy using intracardiac echo 3D reconstruction. Europace. 2004;6(5):407–17.
Chang SL, Tai CT, Lin YJ, Ong MG, Wongcharoen W, Lo LW, Chang SH, et al. The electroanatomic characteristics of the cavotricuspid isthmus: implications for the catheter ablation of atrial flutter. J Cardiovasc Electrophysiol. 2007;18:18–22.
Tai CT, Chen SA, Chiang CE, Lee SH, Ueng KC, Wen ZC, Huang JL, et al. Characterization of low right atrial isthmus as the slow conduction zone and pharmacological target in typical atrial flutter. Circulation. 1997;96:2601–11.
Feld GK, Mollerus M, Birgersdotter-Green U, Fujimura O, Bahnson TD, Boyce K, Rahme M. Conduction velocity in the tricuspid valve-inferior vena cava isthmus is slower in patients with type I atrial flutter compared to those without a history of atrial flutter. J Cardiovasc Electrophysiol. 1997;8:1338–48.
Olgin JE, Kalman JM, Saxon LA, Lee RJ, Lesh MD. Mechanism of initiation of atrial flutter in humans: site of unidirectional block and direction of rotation. J Am Coll Cardiol. 1997;29:376–84.
Poty H, Saoudi N, Abdel Aziz A, Nair M, Letac B. Radiofrequency catheter ablation of type I atrial flutter: prediction of late success by electrophysiological criteria. Circulation. 1995;92:1389–92.
Tada H, Oral H, Sticherling C, Chough SP, Baker RL, Wasmer K, Pelosi Jr F, et al. Double potentials along the ablation line as a guide to radiofrequency ablation of typical atrial flutter. J Am Coll Cardiol. 2001;38:750–5.
Saoudi N, Ricard P, Rinaldi JP, Yaïci K, Darmon JP, Anselme F. Methods to determine bi-directional block of the cavotricuspid isthmus in radiofrequency ablation of typical atrial flutter. J Cardiovasc Electrophysiol. 2005;16:801–3.
Feld G, Wharton M, Plumb V, Daoud E, Friehling T, Epstein L, EPT-1000 XP Cardiac Ablation System Investigators. Radiofrequency catheter ablation of type 1 atrial flutter using large-tip 8 or 10 mm electrode catheter and high-output radiofrequency energy generator: results of a multicenter safety and efficacy study. J Am Coll Cardiol. 2004;43:1466–72.
Costa AD, Cucherat M, Pichon N, Messier M, Laporte S, Romeyer-Bouchard C, Mismetti P. Comparison of the efficacy of cooled tip and 8 mm-tip catheters for radiofrequency catheter ablation of the cavotricuspid isthmus: a metaanalysis. Pacing Clin Electrophysiol. 2005;28:1081–7. Direct Link.
Gk F, Daubert JP, Weiss R, Miles WM, Pelkey W, Cryoablation Atrial Flutter Efficacy Trial Investigators. Acute and long-term efficacy and safety of catheter cryoablation of the cavotricuspid isthmus for treatment of type 1 atrial flutter. Heart Rhythm. 2008;5:1009–14.
Tai CT, Chen SA, Chiang CE, Lee SH, Wen ZC, Huang JL, Chen YJ, et al. Long-term outcome of radiofrequency catheter ablation for typical atrial flutter: risk prediction of recurrent arrhythmias. J Cardiovasc Electrophysiol. 1998;9:115–21.
Paydak H, Kall JG, Burke MC, Rubenstein D, Kopp DE, Verdino RJ, Wilber DJ. Atrial fibrillation after radiofrequency ablation of type I atrial flutter: time to onset, determinants, and clinical course. Circulation. 1998;98:315–22.
Calkins H, Canby R, Weiss R, Taylor G, Wells P, Chinitz L, Milstein S, et al. Results of catheter ablation of typical atrial flutter. Am J Cardiol. 2004;94:437–42.
Ellis K, Wazni O, Marrouche N, Martin D, Gillinov M, McCarthy P, Saad EB, et al. Incidence of atrial fibrillation post-cavotricuspid isthmus ablation in patients with typical atrial flutter: left atrial size as an independent predictor of atrial fibrillation recurrence. J Cardiovasc Electrophysiol. 2007;18:799–802. Direct Link.
Chinitz JS, Gerstenfeld EP, Marchlinski FE, Callans DJ. Atrial fibrillation is common after ablation of isolated atrial flutter during long-term follow-up. Heart Rhythm. 2007;4:1029–33.
Morton JB, Byrne MJ, Power JM. Electrical remodeling of the atrium in an anatomic model of atrial flutter: relationship between substrate and triggers for conversion to atrial fibrillation. Circulation. 2002;105:258–64.
Sparks PB, Jayaprakash S, Vohra JK, Kalman JM. Electrical remodeling of the atria associated with paroxysmal and chronic atrial flutter. Circulation. 2000;102:1807–13.
Da Costa A, Faure E, Thevenin J, et al. Effect of isthmus anatomy and ablation catheter on radiofrequency catheter ablation of the cavotricuspid isthmus. Circulation. 2004;110(9):1030–5.
Jais P, Shah DC, Haissaguerre M, et al. Prospective randomized comparison of irrigated-tip versus conventional-tip catheters for ablation of common flutter. Circulation. 2000;101(7):772–6.
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Chiriac, L., Cristian, G., Bolohan, R., T¸intoiu, I.C. (2014). Cavotricuspid Isthmus Anatomy Particularities in Atrial Flutter Ablation. In: Kibos, A., Knight, B., Essebag, V., Fishberger, S., Slevin, M., Țintoiu, I. (eds) Cardiac Arrhythmias. Springer, London. https://doi.org/10.1007/978-1-4471-5316-0_36
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