Models and Algorithms for Genome Evolution pp 287-307

Part of the Computational Biology book series (COBO, volume 19) | Cite as

The Potential of Family-Free Genome Comparison

  • Marília D. V. Braga
  • Cedric Chauve
  • Daniel Doerr
  • Katharina Jahn
  • Jens Stoye
  • Annelyse Thévenin
  • Roland Wittler

Abstract

Many methods in computational comparative genomics require gene family assignments as a prerequisite. While the biological concept of gene families is well established, their computational prediction remains unreliable. This paper continues a new line of research in which family assignments are not presumed. We study the potential of several family-free approaches in detecting conserved structures, genome rearrangements and in reconstructing ancestral gene orders.

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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • Marília D. V. Braga
    • 1
  • Cedric Chauve
    • 2
    • 3
  • Daniel Doerr
    • 4
    • 5
  • Katharina Jahn
    • 4
    • 5
  • Jens Stoye
    • 4
    • 5
  • Annelyse Thévenin
    • 4
    • 5
  • Roland Wittler
    • 4
    • 5
  1. 1.InmetroDuque de CaxiasBrazil
  2. 2.Department of MathematicsSimon Fraser UniversityBurnabyCanada
  3. 3.LaBRIUniversité Bordeaux ITalenceFrance
  4. 4.Genome Informatics, Faculty of TechnologyBielefeld UniversityBielefeldGermany
  5. 5.Institute for Bioinformatics, CeBiTecBielefeld UniversityBielefeldGermany

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