Abstract
Thyroid Gland Tumours (with comments on Parathyroid): this chapter outlines the incidence, risk factors, clinical presentation, investigations, treatments and prognosis of cancer at this anatomical site. These features are correlated with the core data that are required to make the corresponding histopathology reports of a consistently high quality, available in an appropriate timeframe, and clinically relevant to patient management and prognosis. Summary details of the common cancers given at this site include: gross description, histological types, tumour grade/differentiation, extent of local tumour spread, lymphovascular invasion, lymph node involvement, and the status of excision margins. Current WHO Classifications of Malignant Tumours and TNM7 are referenced. Notes are provided on other associated pathology, contemporary use of immunohistochemistry, updates on the role of evolving molecular tests, and the use of these ancillary techniques as biomarkers in diagnosis, and prediction of prognosis and treatment response. A summary is given of the commoner non-carcinoma malignancies that are encountered at this site in diagnostic practice.
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Bibliography
Allen DC. Histopathology reporting: guidelines for surgical cancer. 2nd ed. London: Springer; 2006.
Anderson CE, McLaren KM. Best practice in thyroid pathology. J Clin Pathol. 2004;56:401–5.
Asa SL. My approach to oncocytic tumours of the thyroid. J Clin Pathol. 2004;57:225–32.
Chetty R. Follicular patterned lesions of the thyroid gland: a practical algorithmic approach. J Clin Pathol. 2011;64:737–41.
De Matos PS. Thyroid epithelial tumours. Diagn Histopathol. 2008;14:236–46.
DeLellis RA, Lloyd RV, Heitz PU, Eng C. WHO classification of tumours. Pathology and genetics. Tumours of endocrine organs. Lyon: IARC Press; 2004.
Derringer GA, Thompson LDR, Frommett RA, Bijwaard KE, Hefess CS, Abbondanzo SL. Malignant lymphoma of the thyroid gland. A clinicopathologic study of 108 cases. Am J Surg Pathol. 2000;24:623–39.
Gnepp DR, editor. Diagnostic surgical pathology of the head and neck. 2nd ed. Philadelphia: WB Saunders; 2009.
Khonsari M, Scarsbrook AF, Bradley KM. Anatomical and functional imaging of the thyroid and parathyroid. CPD Cell Pathol. 2007;6:47–58.
LiVolsi VA, Baloch ZW. Familial thyroid carcinoma: the road less travelled in thyroid pathology. Diagn Histopathol. 2009;15:87–94.
McNichol AM. Criteria for diagnosis of follicular thyroid neoplasms and related conditions. In: Lowe DG, Underwood JCE, editors. Recent advances in histopathology, vol. 20. London: RSM Press; 2003. p. 1–16.
Rosai J, Carcangiu ML, DeLellis RA. Tumors of the thyroid gland. Atlas of tumor pathology. 3rd series. Fascicle 5. Washington: AFIP;. 1992.
Rosai J, Kuhn E, Carcanagiu ML. Pitfalls in thyroid tumour pathology. Histopathology. 2006;49:107–20.
Slootweg PJ. Complex head and neck specimens and neck dissections. How to handle them. ACP best practice no 182. J Clin Pathol. 2005;58:243–8.
Sneed DC. Protocol for the examination of specimens from patients with malignant tumors of the thyroid gland, exclusive of lymphomas. Arch Pathol Lab Med. 1999;123:45–9.
Sobrinho-Simóes M, Magalháes J, Fonseca E, Amendoeira I. Diagnostic pitfalls of thyroid pathology. Curr Diagn Pathol. 2005;11:52–61.
Stephenson TJ. Prognostic and predictive factors in endocrine tumours. Histopathology. 2006;48:629–43.
The Royal College of Pathologists. Head and Neck Tissues – Cancer Datasets (Head and Neck Carcinomas and Salivary Neoplasms, Parathyroid Cancer, Thyroid Cancer) and Tissue Pathways (Head and Neck Pathology, Endocrine Pathology). Accessed at http://www.rcpath.org/index.asp?PageID=254.
Thompson LDR. Endocrine pathology. Philadelphia: Elsevier; 2006.
Parathyroid
DeLellis RA. Tumors of the parathyroid gland. Atlas of tumor pathology. 3rd series. Fascicle 6. Washington: AFIP; 1993.
Erikson LA, Lloyd RV. Familial disorders of the parathyroid gland. Diagn Histopathol. 2009;15:79–88.
Johnson SJ. Changing clinicopathological practice in parathyroid disease. Histopathology. 2010;56:835–51.
Johnson SJ, Sheffield EA, McNichol AM. Examination of parathyroid gland specimens. ACP best practice no 183. J Clin Pathol. 2005;58:338–42.
Stephenson TJ. Prognostic and predictive factors in endocrine tumours. Histopathology. 2006;48:629–43.
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Allen, D.C. (2013). Thyroid Gland Tumours (with Comments on Parathyroid). In: Histopathology Reporting. Springer, London. https://doi.org/10.1007/978-1-4471-5263-7_16
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DOI: https://doi.org/10.1007/978-1-4471-5263-7_16
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