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Measurement of Coronary Flow Reserve in the Catheterization Laboratory

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Physiological Assessment of Coronary Stenoses and the Microcirculation

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Abstract

This chapter starts by a brief review of coronary physiology in terms of pressure-flow relationships and effects of vessel distensibility on microvascular resistance to lay the foundation for interpretation of coronary stenosis hemodynamics. The fluid dynamics of stenosis pressure gradient, resistance, and its dependency on flow and stenosis dimensions is outlined in the next section. Special consideration is given to serial lesions, stenosis compliance, and diffuse coronary narrowing. The last section discusses the hemodynamic effect of coronary epicardial stenoses on coronary blood flow and the need for integration of multiple physiological parameters to arrive at a well-founded procedural decision for an individual patient suffering from ischemic heart disease.

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Authors and Affiliations

  1. Department of Facial Plastic Surgery, Marienhospital Stuttgart, Stuttgart, 70199, Germany

    Tim P. van de Hoef MD & Jan J. Piek MD

Authors
  1. Tim P. van de Hoef MD
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  2. Jan J. Piek MD
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Corresponding authors

Correspondence to Tim P. van de Hoef MD or Jan J. Piek MD .

Editor information

Editors and Affiliations

  1. Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid, Spain

    Javier Escaned

  2. Imperial College London, London, United Kingdom

    Justin Davies

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van de Hoef, T.P., Piek, J.J. (2017). Measurement of Coronary Flow Reserve in the Catheterization Laboratory. In: Escaned, J., Davies, J. (eds) Physiological Assessment of Coronary Stenoses and the Microcirculation. Springer, London. https://doi.org/10.1007/978-1-4471-5245-3_11

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  • DOI: https://doi.org/10.1007/978-1-4471-5245-3_11

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-5244-6

  • Online ISBN: 978-1-4471-5245-3

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