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308 Nanometer Excimer Laser in the Therapy of Peripheral Vascular Disease

Abstract

Excimer laser (308 nm) is presently utilized to treat a wide range of peripheral arterial disease states. It has been used extensively in obstructive disease of the superficial femoral, popliteal, and infra-popliteal vessels. It has been utilized to treat in-stent obstructions as well as graft occlusions. It has been utilized as a crossing tool and an atherectomy device. Advancements in laser technology and technique have resulted in increased utilization. The EXCITE trial has shown laser atherectomy to be superior to PTA for the treatment of SFA in-stent restenosis. Ongoing research utilizing laser atherectomy followed by drug-eluting balloon angioplasty has shown encouraging initial results. Laser results appear to be related as much to improved technique as to improved technology.

Keywords

Laser atherectomy in superficial femoral artery Laser atherectomy in popliteal artery Laser atherectomy in infrapopliteal disease In-stent use of laser atherectomy Laser as a crossing tool Laser in clot Laser as therapy of in-stent stenosis Laser and drug-eluting balloons 

References

  1. 1.
    Walker C, Patlola R, et al. Laser-facilitated lysis of occluded synthetic femoropopliteal bypass grafts. Vasc Dis Manag. 2013;10(3):E63–6.Google Scholar
  2. 2.
    Topaz O et al. “Optimally Spaced” excimer laser coronary catheters: performance analysis. J Clin Laser Med Surg. 2001:19:9–14.Google Scholar
  3. 3.
    Biamino G, Scheinert D. Excimer laser treatment of SFA occlusions. Endovasc Today. 2003;45. Available at: evtoday.com/2003/06/0503_101.html.
  4. 4.
    Laird J. PELA trial: peripheral excimer laser angioplasty. Presented at Transcatheter Cardiovascular Therapeutics 2002. Available at: http://www.medscape.com/viewarticle/442691.
  5. 5.
    Laird JR, Zeller T, Gray BH, et al. Limb salvage following laser-assisted angioplasty for critical limb ischemia: results of the LACI multicenter trial. J Endovasc Ther. 2006;13:1–11.CrossRefPubMedGoogle Scholar
  6. 6.
    Allie D, Walker C. Excimer laser-assisted angioplasty in severe infrapopliteal disease and CLI: the CIS “LACI equivalent” experience. Available at: http://vasculardiseasemanagement.Com/article/3248. Accessed 8 Sept 2008.
  7. 7.
    Dippel E, Dave RM, Patlola R, Kollmeyer K, et al. Excimer laser reconalization of femoropopliteal lesions and 1-year patency: results of the CELLO registry. J Endovasc Ther. 2009;16(6):665–75. doi: 10.1583/09-2781.1.CrossRefPubMedGoogle Scholar
  8. 8.
    Dipple E. Excite trial: the latest data. Presented at New Cardiovascular Horizons 2014, New Orleans, LA.Google Scholar
  9. 9.
    Van den Berg J. 4F lower limb intervention: pulsar stent technology. Presented at New Cardiovascular Horizons 2014, New Orleans, LA.Google Scholar

Copyright information

© Springer-Verlag London 2015

Authors and Affiliations

  1. 1.Cardiovascular Institute of the SouthHoumaUSA
  2. 2.Tulane University School of MedicineNew OrleansUSA
  3. 3.LSU Medical SchoolNew OrleansUSA

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