Associated Conditions

  • Graham Hughes
  • Munther A. Khamashta


The conditions most commonly seen in association with Hughes syndrome are lupus (1 in 5 lupus patients have positive aPL tests and Sjogren’s syndrome (less well studied but probably similar). Other autoimmune diseases, notably Hashimoto’s thyroiditis and autoimmune haemolytic anaemia, are also seen in association with the syndrome.

A rare, severe development is the so-called catastrophic antiphospholipid syndrome (CAPS) in which widespread intravascular thrombosis leads to multi-organ failure.


Celiac Disease Carpal Tunnel Syndrome Recurrent Pregnancy Loss Lupus Patient Intensive Care Department 
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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • Graham Hughes
    • 1
  • Munther A. Khamashta
    • 2
  1. 1.The London Lupus CentreLondon Bridge HospitalLondonUK
  2. 2.Division of Women’s Health, Graham Hughes Lupus Research LaboratoryKing’s College LondonLondonUK

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