Periprocedural Stroke

  • Stephen H. Dorman


Stroke is a rare but devastating complication of percutaneous coronary intervention (PCI). Although a precise causative mechanism is not often established, available literature suggests that over 90 % of strokes or transient ischemic attacks (TIAs) complicating PCI are ischaemic in origin. Despite substantial reductions in other PCI related complications over the last decade, it is noticeable that the incidence of stroke complicating PCI has not changed significantly.


Stroke Cerebrovascular event Embolism Ischaemia Dissection 


  1. 1.
    Fuchs S, Stabile E, Kinnaird TD, Mintz GS, Gruberg L, Canos DA, et al. Stroke complicating percutaneous coronary interventions incidence, predictors, and prognostic implications. Circulation. 2002;106:86–91.CrossRefPubMedGoogle Scholar
  2. 2.
    Aggarwal A, Dai D, Rumsfeld JS, Klein LW, Roe MT. American College of Cardiology National Cardiovascular Data Registry: incidence and predictors of stroke associated with percutaneous coronary intervention. Am J Cardiol. 2009;104:349–53.CrossRefPubMedGoogle Scholar
  3. 3.
    Werner N, Bauer T, Hochadel M, Zahn R, Weidinger F, Marco J, et al. Incidence and clinical impact of stroke complicating percutaneous coronary intervention: results of the Euro heart survey percutaneous coronary interventions registry. Circ Cardiovasc Interv. 2013;6:362–9.CrossRefPubMedGoogle Scholar
  4. 4.
    Lund C, Nes RB, Ugelstad TP, Due-Tønnessen P, Andersen R, Hol PK, et al. Cerebral emboli during left heart catheterization may cause acute brain injury. Eur Heart J. 2005;26:1269–75.CrossRefPubMedGoogle Scholar
  5. 5.
    Kahlert P, Al-Rashid F, Döttger P, Mori K, Plicht B, Wendt D, et al. Cerebral embolization during transcatheter aortic valve implantation: a transcranial Doppler study. Circulation. 2012;126:1245–55.CrossRefPubMedGoogle Scholar
  6. 6.
    Hoffman SJ, Holmes Jr DR, Rabinstein AA, Rihal CS, Gersh BJ, Lennon RJ, et al. Trends, predictors, and outcomes of cerebrovascular events related to percutaneous coronary intervention: a 16-year single-center experience. JACC Cardiovasc Interv. 2011;4:415–22.CrossRefPubMedGoogle Scholar
  7. 7.
    Hoffman SJ, Routledge HC, Lennon RJ, Mustafa MZ, Rihal CS, Gersh BJ, et al. Procedural factors associated with percutaneous coronary intervention–related ischemic stroke. JACC Cardiovasc Interv. 2012;5:200–6.CrossRefPubMedGoogle Scholar
  8. 8.
    Jauch EC, Saver JL, Adams HP, Bruno A, Connors JJ, Demaerschalk BM, et al. Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013;44:870–947.CrossRefPubMedGoogle Scholar
  9. 9.
    Hamon M, Baron J-C, Viader F, Hamon M. Periprocedural stroke and cardiac catheterization. Circulation. 2008;118:678–83.CrossRefPubMedGoogle Scholar
  10. 10.
    Nietlispach F. Cerebral protection devices for transcatheter aortic valve implantation. Cardiovasc Med. 2012;15:287–92.Google Scholar

Copyright information

© Springer-Verlag London 2016

Authors and Affiliations

  1. 1.Department of CardiologyMorriston Cardiac Centre, Morriston HospitalMorristonUK

Personalised recommendations