Abstract
The most common initial symptoms of porphyria cutanea tarda are cutaneous fragility and blistering of the hands, forearms, and, sometimes, the face. erosions may cause epidermal loss and infections. Healing is slow and painful, causing atrophic scars. Cutaneous findings are characterized by skin photosensitivity with increased skin fragility, facial hypertrichosis, blisters, scarring with milia formation, and skin hyperpigmentation on the hands and other sun-exposed areas. Urine sample will often show a grossly discolored with a tea- or wine-colored tint.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Kappas A, Sassa S, Galbraith RA, et al. The porphyrias. In: Scriver CR et al., editors. The metabolic basis of inherited disease. New York: McGraw-Hill; 1995. p. 2103–59.
Moran-Jimenez MJ, Ged C, Romana M, et al. Uroporphyrinogen decarboxylase: complete human gene sequence and molecular study of three families with hepatoerythropoietic porphyria. Am J Hum Genet. 1996;58(4):712–21.
Bonkovsky HL, Lambrecht RW, Shan Y. Iron as a co-morbid factor in nonhemochromatotic liver disease. Alcohol. 2003;30(2):137–44.
Shelly ED, Shelly WD, Burmeister V. Naproxen-induced pseudoporphyria presenting diagnostic dilemma. Cutis. 1987;40:314.
Rocchi E, Cassanelli M, Borghi A, et al. Liver iron overload and desferrioxamine treatment of porphyria cutanea tarda. Dermatologica. 1991;182(1):27–31.
Stolzel U, Kostler E, Schuppan D, et al. Hemochromatosis (HFE) gene mutations and response to chloroquine in porphyria cutanea tarda. Arch Dermatol. 2003;139(3):309–13.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer-Verlag London
About this chapter
Cite this chapter
Norman, R.A., Young, E.M. (2014). Porphyria Cutanea Tarda. In: Atlas of Geriatric Dermatology. Springer, London. https://doi.org/10.1007/978-1-4471-4579-0_10
Download citation
DOI: https://doi.org/10.1007/978-1-4471-4579-0_10
Published:
Publisher Name: Springer, London
Print ISBN: 978-1-4471-4578-3
Online ISBN: 978-1-4471-4579-0
eBook Packages: MedicineMedicine (R0)