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Treatment of Infection in the Diabetic Foot: The Use of Antibiotics

  • Anthony R. Berendt
Chapter

Abstract

Infection in the diabetic foot is a feared complication, and rightly so since it can result in amputation; infection is associated with amputation either as a final insult to the foot on top of other pre-existing problems, or as an overwhelming and destructive acute event necessitating amputation in its own right. The management of diabetic foot infection requires a multi-disciplinary approach and antibiotics, a focus of this chapter, are usually necessary, but rarely sufficient, to control infection and it consequences. This chapter highlights the fact that consideration of the role of antibiotics must be part of a more general understanding of all other essential steps in the management of infection in the diabetic foot.

Keywords

Diabetic foot infection Diabetic foot ulcers Wound infection Antibiotic therapy Wound care 

References

  1. 1.
    Lipsky BA, Peters EJG, Senneville E, Berendt AR, Embil JM, Lavery LA, et al. Expert opinion on the management of infections in the diabetic foot. Diabetes Metab Res Rev. 2012;28 Suppl 1:163–78.PubMedCrossRefGoogle Scholar
  2. 2.
    Lipsky BA, Berendt AR, Cornia PB, Pile JC, Peters EJG, Armstrong DG, Deery HG, Embil JM, Joseph WS, Karchmer AW, Pinzur MS, Senneville E. 2012 Infectious Disease Society of America clinical practice guideline for diagnosis and treatment of diabetic foot infections. Clin Infect Dis. 2012;54(12):132–73.CrossRefGoogle Scholar

Suggested Reading

  1. Diabetic foot problems: inpatient management of diabetic foot problems. www.nice.org.uk/guidance/CG119.
  2. Lipsky BA, Berendt AR, Deery HR, Embil JM, Joseph WS, Karchmer AW, et al. Diagnosis and treatment of diabetic foot infections. Clin Infect Dis. 2004;39:885–910.PubMedCrossRefGoogle Scholar
  3. Peters EJG, Lipsky BA, Berendt AR, Embil JM, Lavery LA, Senneville E, et al. A systematic review of the effectiveness of interventions in the management of infection in the diabetic foot. Diabetes Metab Res Rev. 2012;28 Suppl 1:142–62.PubMedCrossRefGoogle Scholar
  4. Richard J-L, Lavigne J-P, Sotto A. Diabetes and foot infection: more than double trouble. Diabetes Metab Res Rev. 2012;28 Suppl 1:46–53.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London 2015

Authors and Affiliations

  1. 1.Bone Infection UnitNuffield Orthopaedic Centre, Oxford University Hospitals NHS TrustOxfordUK

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