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Monilethrix, Pseudomonilethrix, and Monilethrix-Like Hairs

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Abstract

In monilethrix, trichoscopy shows abnormalities in terminal and vellus hairs of the scalp. Hair shafts show uniform elliptical nodosities and intermittent constrictions causing regular variation in hair shaft thickness. Hairs bend and break at constriction sites. Horny follicular papules appear as big yellow dots when evaluated on trichoscopy with immersion fluid. Perifollicular scaling and keratotic follicular plugs are be best visible on dry trichoscopy. Differential diagnosis includes monilethrix-like congenital hypotrichosis, pseudomonilethrix, and acquired monilethrix-like hair shaft appearance.

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References

  1. Neila Iglesias J, Rodriguez Pichardo A, Garcia Bravo B, Camacho Martinez F. Masquerading of trichotillomania in a family with monilethrix. Eur J Dermatol. 2011;21(1):133.

    PubMed  Google Scholar 

  2. Djabali K, Panteleyev AA, Lalin T, Garzon MC, Longley BJ, Bickers DR, et al. Recurrent missense mutations in the hair keratin gene hHb6 in monilethrix. Clin Exp Dermatol. 2003;28(2):206–10.

    Article  PubMed  CAS  Google Scholar 

  3. Shimomura Y, Sakamoto F, Kariya N, Matsunaga K, Ito M. Mutations in the desmoglein 4 gene are associated with monilethrix-like ­congenital hypotrichosis. J Invest Dermatol. 2006;126(6):1281–5.

    Article  PubMed  CAS  Google Scholar 

  4. Farooq M, Ito M, Naito M, Shimomura Y. A case of monilethrix caused by novel compound heterozygous mutations in the desmoglein 4 (DSG4) gene. Br J Dermatol. 2011;165(2):425–31.

    Article  PubMed  CAS  Google Scholar 

  5. Zlotogorski A, Marek D, Horev L, Abu A, Ben-Amitai D, Gerad L, et al. An autosomal recessive form of monilethrix is caused by mutations in DSG4: clinical overlap with localized autosomal recessive hypotrichosis. J Invest Dermatol. 2006;126(6):1292–6.

    Article  PubMed  CAS  Google Scholar 

  6. Mirmirani P, Huang KP, Price VH. A practical, algorithmic approach to diagnosing hair shaft disorders. Int J Dermatol. 2011;50(1):1–12.

    Article  PubMed  Google Scholar 

  7. Rakowska A, Slowinska M, Kowalska-Oledzka E, Rudnicka L. Trichoscopy in genetic hair shaft abnormalities. J Dermatol Case Rep. 2008;2(2):14–20.

    Article  PubMed  Google Scholar 

  8. Rakowska A, Slowinska M, Czuwara J, Olszewska M, Rudnicka L. Dermoscopy as a tool for rapid diagnosis of monilethrix. J Drugs Dermatol. 2007;6(2):222–4.

    PubMed  Google Scholar 

  9. Wallace MP, de Berker DA. Hair diagnoses and signs: the use of dermatoscopy. Clin Exp Dermatol. 2010;35(1):41–6.

    Article  PubMed  CAS  Google Scholar 

  10. Jain N, Khopkar U. Monilethrix in pattern distribution in siblings: diagnosis by trichoscopy. Int J Trichol. 2010;2(1):56–9.

    Article  Google Scholar 

  11. Zitelli JA. Pseudomonilethrix. An artifact. Arch Dermatol. 1986;122(6):688–90.

    Article  PubMed  CAS  Google Scholar 

  12. Itin PH, Schiller P, Mathys D, Guggenheim R. Cosmetically induced hair beads. J Am Acad Dermatol. 1997;36(2 Pt 1):260–1.

    Article  PubMed  CAS  Google Scholar 

  13. Trueb RM. Chemotherapy-induced alopecia. Curr Opin Support Palliat Care. 2010;4(4):281–4.

    Article  PubMed  Google Scholar 

  14. Yeager CE, Olsen EA. Treatment of chemotherapy-induced ­alopecia. Dermatol Ther. 2011;24(4):432–42.

    Article  PubMed  Google Scholar 

  15. Blume-Peytavi U, Fohles J, Schulz R, Wortmann G, Gollnick H, Orfanos CE. Hypotrichosis, hair structure defects, hypercysteine hair and glucosuria: a new genetic syndrome? Br J Dermatol. 1996;134(2):319–24.

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Lidia Rudnicka .

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© 2012 Springer-Verlag London

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Rakowska, A., Rudnicka, L. (2012). Monilethrix, Pseudomonilethrix, and Monilethrix-Like Hairs. In: Rudnicka, L., Olszewska, M., Rakowska, A. (eds) Atlas of Trichoscopy. Springer, London. https://doi.org/10.1007/978-1-4471-4486-1_8

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  • DOI: https://doi.org/10.1007/978-1-4471-4486-1_8

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-4485-4

  • Online ISBN: 978-1-4471-4486-1

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