Woolly Hair

Chapter

Abstract

In woolly hair, trichoscopy demonstrates hair shafts with waves at very short intervals, giving the hair a “crawling snake” appearance. Hair shaft thickness appears uneven because of the twists that are typical for this condition. Entangled and broken hairs may be present. Trichoscopy is not decisive for diagnosis.

Keywords

Black dots Broken hairs Cicatricial alopecia Pili annulati Trichorrhexis nodosa Woolly hair 

References

  1. 1.
    Chien AJ, Valentine MC, Sybert VP. Hereditary woolly hair and keratosis pilaris. J Am Acad Dermatol. 2006;54(2 Suppl):S35–9.PubMedCrossRefGoogle Scholar
  2. 2.
    Jimenez-Sanchez MD, Garcia-Hernandez MJ, Camacho FM. Woolly hair with alopecia areata in a Caucasian girl. Eur J Dermatol. 2010;20(2):245–6.PubMedGoogle Scholar
  3. 3.
    Hutchinson PE, Cairns RJ, Wells RS. Woolly hair. Clinical and general aspects. Trans St Johns Hosp Dermatol Soc. 1974;60(2):160–77.PubMedGoogle Scholar
  4. 4.
    Horev L, Tosti A, Rosen I, Hershko K, Vincenzi C, Nanova K, et al. Mutations in lipase H cause autosomal recessive hypotrichosis simplex with woolly hair. J Am Acad Dermatol. 2009;61(5):813–8.PubMedCrossRefGoogle Scholar
  5. 5.
    Horev L, Babay S, Ramot Y, Saad-Edin B, Moorad S, Ingber A, et al. Mutations in two genes on chromosome 13 resulting in a complex hair and skin phenotype due to two rare genodermatoses: KLICK and autosomal recessive woolly hair/hypotrichosis simplex. Br J Dermatol. 2011;164(5):1113–6.PubMedCrossRefGoogle Scholar
  6. 6.
    Horev L, Saad-Edin B, Ingber A, Zlotogorski A. A novel deletion mutation in P2RY5/LPA(6) gene cause autosomal recessive woolly hair with hypotrichosis. J Eur Acad Dermatol Venereol. 2010;24(7):858–9.PubMedCrossRefGoogle Scholar
  7. 7.
    Shimomura Y, Wajid M, Ishii Y, Shapiro L, Petukhova L, Gordon D, et al. Disruption of P2RY5, an orphan G protein-coupled receptor, underlies autosomal recessive woolly hair. Nat Genet. 2008;40(3):335–9.PubMedCrossRefGoogle Scholar
  8. 8.
    Shimomura Y, Ito M, Christiano AM. Mutations in the LIPH gene in three Japanese families with autosomal recessive woolly hair/hypotrichosis. J Dermatol Sci. 2009;56(3):205–7.PubMedCrossRefGoogle Scholar
  9. 9.
    Shimomura Y, Wajid M, Petukhova L, Kurban M, Christiano AM. Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture. Am J Hum Genet. 2010;86(4):632–8. PMCID: 2850421.PubMedCrossRefGoogle Scholar
  10. 10.
    Bolling MC, Jonkman MF. Skin and heart: une liaison dangereuse. Exp Dermatol. 2009;18(8):658–68.PubMedCrossRefGoogle Scholar
  11. 11.
    Koumantaki E, Gregoriou S, Kakrida M, Christofidou E, Katsambas A. What is your diagnosis? Diffuse nonepidermolytic palmoplantar keratoderma with woolly hair and cardiomyopathy (Naxos-Carvajal syndrome). Cutis. 2010;85(4):180, 9–90.PubMedGoogle Scholar
  12. 12.
    Al-Owain M, Wakil S, Shareef F, Al-Fatani A, Hamadah E, Haider M, et al. Novel homozygous mutation in DSP causing skin ­fragility-woolly hair syndrome: report of a large family and review of the desmoplakin-related phenotypes. Clin Genet. 2011;80(1):50–8.PubMedCrossRefGoogle Scholar
  13. 13.
    Weiss G, Confino Y, Shemer A, Trau H. Cutaneous manifestations in the cardiofaciocutaneous syndrome, a variant of the classical Noonan syndrome. Report of a case and review of the literature. J Eur Acad Dermatol Venereol. 2004;18(3):324–7.PubMedCrossRefGoogle Scholar
  14. 14.
    Tharini GK, Hema N, Jayakumar S, Parveen B. Olmsted syndrome: report of two cases. Indian J Dermatol. 2011;56(5):591–3.PubMedCrossRefGoogle Scholar
  15. 15.
    Kumaran S, Dogra S, Handa S, Kanwar AJ. Woolly hair nevus. Pediatr Dermatol. 2004;21(5):609–10.PubMedCrossRefGoogle Scholar
  16. 16.
    Rakowska A, Slowinska M, Kowalska-Oledzka E, Rudnicka L. Trichoscopy in genetic hair shaft abnormalities. J Dermatol Case Rep. 2008;2(2):14–20.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London 2012

Authors and Affiliations

  1. 1.Department of DermatologyCSK MSWWarsawPoland
  2. 2.Department of DermatologyMedical University of WarsawWarsawPoland

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