Platelet Activation After Lung Transplantation

Chapter

Abstract

Initially recognized for their central role in thrombosis, there has been an emerging understanding that platelets also play an important role in both the innate as well as the adaptive immune response. The profound impact and putative role of platelet activation in both acute and chronic allograft failure after lung transplant are just beginning to be truly appreciated. To understand this multifactorial interaction, one must first understand the basics of platelet physiology.

Keywords

Permeability Migration Ischemia Creatinine Aspirin 

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Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  1. 1.Lung Transplant ProgramHenry Ford Health SystemDetroitUSA
  2. 2.Lung Transplant Program, General Thoracic SurgeryColumbia University Medical CenterNew YorkUSA

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