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The Systemic Inflammatory Response Syndrome Following Cardiopulmonary Bypass in Children

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Abstract

The systemic inflammatory response syndrome (SIRS) is multifaceted. In open-heart surgery, the surgical trauma is a contributor, but even more important is the use of cardiopulmonary bypass. After cardiac repair, reperfusion of the heart and lungs also contributes to the inflammatory response. The consequences of SIRS may be deleterious and sometimes even fatal. However, this is very rare in today’s routine surgery for congenital heart disease. It is obvious that all means to reduce SIRS should be undertaken because this factor contributes most to postoperative mortality and morbidity.

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  1. Department of Thoracic and Cardiovascular Surgery, University of Oslo, Rikshospitalet University Hospital, Oslo, Norway

    Harald L. Lindberg MD, PhD & Tom N. Hoel MD, PhD

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  1. Harald L. Lindberg MD, PhD
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Correspondence to Harald L. Lindberg MD, PhD .

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  1. University Nove de Julho, Melo Alves 685, São Paulo, 01417-010, São Paulo, Brazil

    Edmo Atique Gabriel

  2. Pontifícia Universidade Católica de Camp, Rodovia D. Pedro I, km 136, São Paulo, 13086-900, São Paulo, Brazil

    Sthefano Atique Gabriel

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Lindberg, H.L., Hoel, T.N. (2013). The Systemic Inflammatory Response Syndrome Following Cardiopulmonary Bypass in Children. In: Gabriel, E., Gabriel, S. (eds) Inflammatory Response in Cardiovascular Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-4429-8_28

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