The somatosensory system processes four broadly distinct sensory modalities: tactile, proprioceptive, thermal sensations, and pain. Interspersed between the delivery of a noxious stimulus and the subjective dimension of pain is a series of complex chemical and electrical events including local positive feed forward and negative feedback circuits, neuronal networks, and the involvement of several brain modules, including those of the vegetative nervous system. Pain stimulates different physiological responses like increased breathing, heart rate, blood pressure, sweating, and general arousal. Pain is a multidimensional phenomenon being influenced and stimulating different further body systems.
KeywordsFatigue Depression Ischemia Migraine Cortisol
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