A Rare and Severe Variant of a Common Disease

  • Mohammad Ali El-Darouti


A 37-year-old male presented with recurrent and persistent folliculitis associated with suppurative nodules and pyoderma gangrenosum-like ulcers, for duration of 20 years. Lesions were most extensive on the trunk (Fig. 56.1). Other involved areas were the face, upper arms, and the root of the penis (Figs. 56.2, 56.3, and 56.4). Lesions were associated with fever, bone pain, weight loss. He had renal failure 5 years prior to presentation and there was a history of severe nodulocystic acne.


Bone Pain Congenital Adrenal Hyperplasia Pyoderma Gangrenosum Infectious Mononucleosis Suppurative Nodule 
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  1. Allison MA, Dunn CL, Person DA. Acne fulminans treated with isotretinoin and “pulse” corticosteroids. Pediatr Dermatol. 1997;14(1):39–42.PubMedCrossRefGoogle Scholar
  2. Choi EH, Bang D. Acne fulminansand 13-cis-retinoic acid. J Dermatol. 1992;19:378–83.PubMedGoogle Scholar
  3. Cunliffe WJ, Gollnick H. Acne fulminans. In: Cunliffe WJ, Gollnick H, editors. Acne: diagnosis and management. London: Martin Dunitz Ltd; 2001. p. 84–6.Google Scholar
  4. Gordon PM, Farr PM, Milligan A. Acnefulminans and bone lesions may present to other specialties. Pediatr Dermatol. 1997;14(6):446–8.PubMedCrossRefGoogle Scholar
  5. Heydenreich G. Testosterone and anabolic steroids and acne fulminans. Arch Dermatol. 1989;125(4):571–2.PubMedCrossRefGoogle Scholar
  6. Honma M, Murakami M, Iinuma S, et al. Acne fulminans following measles infection. J Dermatol. 2009;36(8):471–3.PubMedCrossRefGoogle Scholar
  7. Jansen T, Plewig G. Acne fulminans. Int J Dermatol. 1998;37:254–7.PubMedCrossRefGoogle Scholar
  8. Jansen T, Romiti R, Woitalla S, et al. Eruptive acne vulgaris with infectious mononucleosis. Br J Dermatol. 2000;142:837–8.PubMedCrossRefGoogle Scholar
  9. Lane JM, Leyden JJ, Spiegel RJ. Acne arthralgia. J Bone Joint Surg Am. 1976;58:673–5.Google Scholar
  10. Palatsi R, Oikarinen A. Hormonal analysis and delayed hypersensitivity reactions in identical twins with severe acne. Acta Derm Venereol. 1979;59(2):157–60.PubMedGoogle Scholar
  11. Placzek M, Degitz K, Schmidt H, Plewig G. Acne fulminans in late-onset congenital adrenal hyperplasia. Lancet. 1999;354(9180):739–40.PubMedCrossRefGoogle Scholar
  12. Seukeran DC, Cunliffe WJ. The treatment of acne fulminans: a review of 25 cases. Br J Dermatol. 1999;141(2):307–9.PubMedCrossRefGoogle Scholar
  13. Tan BB, Lear JT, Smith AG. Acne fulminans and erythema nodosum during isotretinoin therapy responding to dapsone. Clin Exp Dermatol. 1997;22:26–7.PubMedCrossRefGoogle Scholar
  14. Williamson DM, Cunliffe WJ, Gatecliff M, et al. Acute ulcerative acne conglobata (acne fulminans) with erythema nodosum. Clin Exp Dermatol. 1977;2(4):351–4.PubMedCrossRefGoogle Scholar
  15. Zaba R, Schwartz R, Jarmuda S, Czarnecka-Operacz M, Silny W. Acne fulminans: explosive systemic form of acne. J Eur Acad Dermatol Venereol. 2011;25(5):501–7. doi: 10.1111/j.1468-3083.2010.03855.x.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London 2013

Authors and Affiliations

  • Mohammad Ali El-Darouti
    • 1
  1. 1.Cairo UniversityCairoEgypt

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