Introduction to Hypermobility

  • Peter Beighton
  • Rodney Grahame
  • Howard Bird

Abstract

The first clinical description of articular hypermobility is attributed to Hippocrates, who, in the fourth century B.C., described the Scythians, a race of people inhabiting the region that now forms the Ukraine and Czechoslovakia, as having humidity, flabbiness and atony such that they were unable to use their weapons. Their main problem in warfare was that hyperlaxity of the elbow and shoulder joints prevented them from drawing their bows effectively.

Keywords

Arthritis Torque Neuropathy Osteoarthritis Prednisolone 

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References

  1. Ansell BM (1972) Hypermobility of joints. Mod Trends Orthop 6: 419–425Google Scholar
  2. Barnett CH (1971) The mobility of synovial joints. Rheumatol Phys Med 11: 20–27PubMedCrossRefGoogle Scholar
  3. Beighton PH, Price A, Lord J, Dickson E (1969) Variants of the Ehlers-Danlos Syndrome. Clinical, chemical, haematological and chromosomal features of 100 patients. Ann Rheum Dis 28: 228–240PubMedCrossRefGoogle Scholar
  4. Beighton PH, Solomon L, Soskolne CL (1973) Articular mobility in an African population. Ann Rheum Dis 32: 413–418PubMedCrossRefGoogle Scholar
  5. Beighton PH et al. (1988) International nosology of heritable disorders of connective tissue, Berlin 1986. Am J Med Genet 29: 581–594PubMedCrossRefGoogle Scholar
  6. Bird HA, Tribe CR, Bacon PA (1978) Joint hypermobility leading to osteoarthrosis and chrondrocalcinosis. Ann Rheum Dis 37: 203–211PubMedCrossRefGoogle Scholar
  7. Carter C, Sweetnam R (1958) Familial joint laxity and recurrent dislocation of the patella. J Bone Joint Surg [Br] 40: 664–667Google Scholar
  8. Carter C, Sweetnam R (1960) Recurrent dislocation of the patella and of the shoulder. J Bone Joint Surg [Br] 46: 40–45Google Scholar
  9. Carter C, Wilkinson J (1964) Persistent joint laxity and congenital dislocation of the hip. J Bone Joint Surg [Br] 46: 40–45Google Scholar
  10. Child AH (1986) Joint hypermobility syndrome: inherited disorder of collagen synthesis. J Rheumato 113: 239–243Google Scholar
  11. Fairbank JCT, Pynsent PB, Phillips H (1984) Quantitative measurement of joint mobility in adolescents. Ann Rheum Dis 43: 288–294PubMedCrossRefGoogle Scholar
  12. Finkelstein H (1916) Joint hypotonia. NY Med J 104: 942–943Google Scholar
  13. Gedalia A, Person DA, Brewer EJ, Giannini EH (1985) Juvenile episodic arthralgia and hypermobility. J Pediatr 107: 873–876PubMedCrossRefGoogle Scholar
  14. Grahame R (1970) A method for measuring human skin elasticity in vivo with observations on the effects of age, sex and pregnancy. Clin Sci 39: 223–233PubMedGoogle Scholar
  15. Grahame R, Beighton P (1969) Physical properties of the skin in the Ehlers-Danlos syndrome. Ann Rheum Dis 28: 246–252PubMedCrossRefGoogle Scholar
  16. Grahame R, Jenkins JM (1972) Joint hypermobility–asset or liability. Ann Rheum Dis 31: 109–111PubMedCrossRefGoogle Scholar
  17. Harris H, Joseph J (1949) Variation and extension of the metacarpophalangeal and interphalangeal joints of the thumb. J Bone Joint Surg [Br] 31: 547–559Google Scholar
  18. Horan FT, Beighton PH (1973) Recessive inheritance of generalised joint hypermobility. Rheumatol Rehabil 12: 47–49PubMedCrossRefGoogle Scholar
  19. Howes RJ, Isdale IC (1971) The loose back: an unrecognised syndrome. Rheumatol Phys Med 11: 72–77PubMedCrossRefGoogle Scholar
  20. Key JA (1927) Hypermobility of joints as a sex linked hereditary characteristic. JAMA 88: 1710–1712CrossRefGoogle Scholar
  21. Kirk JH, Ansell BM, Bywaters EGL (1967) The hypermobility syndrome. Ann Rheum Dis 26: 419–425PubMedCrossRefGoogle Scholar
  22. Larsson LG, Baum J, Mudholkar GS (1987) Hypermobility: features and differential incidence between the sexes. Arthritis Rheum 30: 1426–1430PubMedCrossRefGoogle Scholar
  23. Lewkonia RM (1987) Hypermobility of joints. Arch Dis Child 62: 1–2PubMedCrossRefGoogle Scholar
  24. Lewkonia RM, Ansell BM (1983) Articular hypermobility simulating chronic rheumatic disease. Arch Dis Child 58: 988–991PubMedCrossRefGoogle Scholar
  25. Massie WK, Howarth MB (1951) Congenital dislocation of the hip. J Bone Joint Surg [Am] 33: 171–198Google Scholar
  26. McKusick VA (1986) Mendelian inheritance in man. Catalogs of autosomal dominant, autosomal recessive and X-linked phenotype, 7th edn. Johns Hopkins University Press, BaltimoreGoogle Scholar
  27. Silverman S, Constine L, Harvey W, Grahame R (1975) Survey of joint mobility and in vivo skin elasticity in London school children. Ann Rheum Dis 34: 177–180PubMedCrossRefGoogle Scholar
  28. Sutro J (1947) Hypermobility of knees due to overlengthened capsular and ligamentous tissues. Surgery 21: 67–76PubMedGoogle Scholar
  29. Troup JDG, Hood CA, Chapman AE (1968) Measurements of the sagittal mobility of the lumbar spine and hips. Ann Phys Med 9: 308–321PubMedGoogle Scholar
  30. Wood PHN (1971) Is hypermobility a discrete entity? Proc R Soc Med 64: 690–692PubMedGoogle Scholar
  31. Wordsworth P, Ogilvie D, Smith R, Sykes B (1987) Joint mobility with particular reference to racial variation and inherited connective tissue disorders. Br J Rhéumatol 26: 9–12PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1989

Authors and Affiliations

  • Peter Beighton
    • 1
  • Rodney Grahame
    • 2
  • Howard Bird
    • 3
  1. 1.MRC Research Unit for Inherited Skeletal Disorders, Medical School and Groot Schuur HospitalUniversity of Cape TownSouth Africa
  2. 2.Rheumatology Unit, Division of Medicine, United Medical and Dental SchoolsGuy’s HospitalLondonUK
  3. 3.Royal Bath HospitalUniversity of Leeds, and Clinical Pharmacology Unit (Rheumatism Research)HarrogateUK

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