Eicosanoid Dependent and Independent Effects of n-3 Fatty Acids on Platelets and Vascular Function

  • G. A. FitzGerald
Conference paper
Part of the Current Topics in Cardiovascular Diseases book series (2943)


Fish oils have been recognized as potentially important modulators of platelet function and vascular tone. Initially, their influence on eicosanoid synthesis was believed to be responsible for most, if not all, of their physiological effects. However, more recent evidence has challenged this view and the principal data on this subject will be reviewed.


Eicosapentaenoic Acid Epoxyeicosatrienoic Acid Arachidonic Acid Incorporation PGI2 Synthesis Polyunsaturated Fatty Acid Supplement 
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Copyright information

© Springer-Verlag London 1992

Authors and Affiliations

  • G. A. FitzGerald
    • 1
  1. 1.Center for Cardiovascular Science, Department of Medicine and Experimental TherapeuticsUniversity College Dublin, Mater HospitalDublinIreland

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