Determinants of Echo-Doppler Indices of Left Ventricular Filling in Patients with Chronic Lung Diseases

  • A. Torbicki
  • I. Hawrylkiewicz
  • Z. Miskiewicz
  • T. Pasierski
  • K. Skwarski
  • R. Tramarin
  • J. Zielinski
Part of the Current Topics in Rehabilitation book series (CURRENT REHAB)


Consequences of chronic lung diseases on left ventricular (LV) diastolic function have not been extensively studied.1 Recent communications suggested, that LV filling in patients with COPD may be abnorma1.2,3 Louie et al. using Doppler echocardiography found evidence of left ventricular (LV) diastolic dysfunction in patients with primary pulmonary hypertension.4


Pulmonary Hypertension Chronic Lung Disease Pulmonary Arterial Pressure Left Ventricular Filling Primary Pulmonary Hypertension 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Morpurgo M., Denolin H.: The heart in pulmonary hypertension due to lung disease. In: Wagenvoort C.A., Denolin H. (Eds.) Pulmonary Circulation. Amsterdam, Elsevier Science Publishers BV 1989; p. 163–189Google Scholar
  2. 2.
    Assayag P., Brochet E., Faraggi M., Mal H., Gamerman G., Pariente R., Valere P.E.: Left ventricular filling impairment in chronic obstructive lung disease with right ventricular pressure overload. (abstr). Eur. Heart J. 1989; 10–8Google Scholar
  3. 3.
    Song G.J., Jones C.J.H., Oldershaw P.J.: Mechanism of left ventricular diastolic dysfunction in cor pulmonale–the role of interventricular transmission of raised right ventricular pressure (abstr). Eur. Heart J. 1989; 10–8Google Scholar
  4. 4.
    Louie E.K., Rich S., Brundage B.H.: Doppler echocardiographic assessment of impaired left ventricular filling in patients with right ventricular pressure overload due to pulmonary hypertension. Am. J. Cardiol. 1986; 8: 1298–1306CrossRefGoogle Scholar
  5. 5.
    Rokey R., Kuo L.C., Zoghbi W.A., Limacher M.C., Quinones M.A.: Determination of parameters of diastolic filling with pulsed Doppler echocardiography: comparison with cineangiography. Circulation 1985; 71: 543–550PubMedCrossRefGoogle Scholar
  6. 6.
    Snider A.R., Gidding S.S., Rocchini A.P., Rosenthal A., Dick M., Crowley D.C., Peters J.: Doppler evaluation of left ventricular diastolic filling in children with systemic hypertension. Am. J. Cardiol. 1985; 56: 921–926PubMedCrossRefGoogle Scholar
  7. 7.
    Hatle L.K., Angelsen B.: Doppler ultrasound in cardiology: physical principles and clinical applications. Philadelphia, Lea and Febiger, 2nd edition, 1985Google Scholar
  8. 8.
    Labovitz A.J., Williams G.A.: Doppler Echocardiography. The Quantitative Approach. Philadelphia, Lea and Febiger 1989; p. 85–100Google Scholar
  9. 9.
    Appleton C.P., Hatle L.K., Popp R.L.: Relation of transmitral flow velocity patterns to left ventricular diastolic function. New insights from a combined hemodynamic and Doppler echocardiographic study. J. Am. Coll. Cardiol. 1988; 12: 426–440PubMedCrossRefGoogle Scholar
  10. 10.
    Hsieh K.S., Sanders S.P., Colan S.D., MacPherson D., Holland C.: Right ventricular systolic time intervals: comparison of echocardiographic and Doppler derived values. Am. Heart J. 1986; 112: 103–106PubMedCrossRefGoogle Scholar
  11. 11.
    Torbicki A., Hawrylkiewicz I., Zielinski J.: Value of M-mode echocardiography in assessing pulmonary arterial pressure in patients with chronic lung disease. Bull. Eur. Physiopathol. Respir. 1987; 23: 233–239PubMedGoogle Scholar
  12. 12.
    Torbicki A., Skwarski K., Hawrylkiewicz I., Pasierski T., Miskiewicz Z., Zielinski J.: Attempts at measuring pulmonary arterial pressure with Doppler echocardiography in patients with chronic lung diseases. Eur. Respir. J. 1989Google Scholar
  13. 13.
    Morpurgo M., Saviotti M., Dickele M.C., Casazza F., Torbicki A., Weitzenblum E., Zielinski J.: Echocardiographic aspects of pulmonary hypertension in chronic lung disease. Bull. Eur. Physiopath. Respir. 1984; 20: 251–255Google Scholar
  14. 14.
    Riggs T.W., Snider A.R.: Respiratory influence on RV and LV diastolic filling in normal children (abstr). J. Am. Coll. Cardiol. 1989; 13: 205AGoogle Scholar
  15. 15.
    Uiterval C., Van Dam I., De Boo Th., Van Keulen P., Folgering H., Hopman J, Daniels O.: The effect of respiration on diastolic blood flow velocities in the human heart. Eur. Heart. J. 1989; 10: 108–112Google Scholar
  16. 16.
    Scharf S.M.: Effects of normal and stressed inspiration on cardiovascular function. In: Scharf S.M., Cassidy S.S. (Eds) Heart-lung interactions in health and disease New York, Basel, Marcel Dekker Inc. 1989; p. 427–461Google Scholar
  17. 17.
    Lloyd T.C.: Mechanical heart-lung interactions. In: Scharf S.M., Cassidy S.S. (Eds) Heart-lung interactions in health and disease. New York-Basel, Marcel Dekker, 1989; p. 309–336Google Scholar
  18. 18.
    Miyatake K., Okamoto M., Kinoshita N., Owa M., Nakasone I., Sakakibara H., Nimura Y.: Augmentation of atrial contribution to left ventricular inflow with ageing as assessed by intracardiac Doppler flowmetry. Am. J. Cardiol. 1984; 53: 586–589PubMedCrossRefGoogle Scholar
  19. 19.
    Miller T.R., Grossman S.J., Schectman K.B., Biello D.R., Ludbrook P.A., Ehsani A.A.: Left ventricular diastolic filling and its association with age. Am. J. Cardiol. 1986; 58: 531–535PubMedCrossRefGoogle Scholar
  20. 20.
    Kuo L.C., Quinones M.A., Rokey R., Sartori M., Abinader E.G., Zoghbi W.A.: Quantification of atrial contribution to left ventricular filling by pulsed Doppler echocardiography and the effect of age in normal and diseased hearts. Am. J. Cardiol. 1987; 59: 1174–1178PubMedCrossRefGoogle Scholar
  21. 21.
    Burstin L.: Determination of pressure in the pulmonary artery by external graphic recordings. Br. Heart J. 1967; 29: 396–404PubMedCrossRefGoogle Scholar
  22. 22.
    Hatle L., Angelsen B.A.J., Tromsdal A.: Noninvasive estimation of pulmonary artery systolic pressure with Doppler ultrasound. Br. Heart J. 1981; 45: 157–165PubMedCrossRefGoogle Scholar
  23. 23.
    Triffon D., Groves B.M., Reeves J.T., Ditchey R.V.: Determinants of the relation between systolic pressure and duration of isovolumic relaxation in the right ventricle. J. Am. Coll. Cardiol. 1988; 11: 322–329PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London 1992

Authors and Affiliations

  • A. Torbicki
    • 1
  • I. Hawrylkiewicz
    • 2
  • Z. Miskiewicz
    • 1
  • T. Pasierski
    • 1
  • K. Skwarski
    • 2
  • R. Tramarin
    • 3
  • J. Zielinski
    • 2
  1. 1.Department of Hypertension and AngiologyAcademy of MedicineWarsawPoland
  2. 2.Department of Respiratory Medicine, Institute of Tuberculosis and Lung DiseasesUniversity HospitalWarsawPoland
  3. 3.Division of Cardiology, Clinica del Lavoro Foundation, Institute of Care and ResearchMedical Center of RehabilitationMontescanoItaly

Personalised recommendations