Advertisement

Long Bone Metastasis

  • B. T. Allende
  • B. L. Allende
Chapter

Abstract

Malignant metastatic tumors are the most common bone neoplasms. The skeleton is often affected by metastasic cancer, and the discovery of a long-bone metastasis may be the first symptom of the primary disease. Nearly every malignant neoplasm has been described as having the capability to metastasize to bone; tumors of breast, prostate, thyroid, lung, and kidney are the most common bone-seeking malignant lesions, and between 50 and 85% of affected patients will have bone metastasis at one point of their disease [1,2,3]. Breast and prostate cancer alone account for more than 80% of metastasic bone disease. The capacity of the neoplastic cells to invade bone is related to the histology and to the aggressiveness of the primary tumor.

Keywords

Internal Fixation Proximal Femur Pathologic Fracture Intramedullary Nail Compression Screw 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    O’Connor MI. Symposium: Metastatic bone disease. In: Program and abstracts of the 67th annual meeting of the American Academy of Orthopaedic Surgeons; March 15–19, 2000; Orlando, USA.Google Scholar
  2. 2.
    Sim F. Diagnosis and Management of Metastatic Bone Disease: A Multidisciplinary Approach. New York: Raven Press, 1988.Google Scholar
  3. 3.
    Coleman R. Skeletal complications of malignancy. Cancer 1997;80(suppl 8):1588–94.PubMedCrossRefGoogle Scholar
  4. 4.
    Diel I, Solomayer E, Costa S. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. N Engl J Med 1998;339:357–63.PubMedCrossRefGoogle Scholar
  5. 5.
    Mirelis H. Metastasic disease in long bones: A proposed scoring system for diagnosing impending pathologic fractures. Clin Orthop 1989;249:256–64.Google Scholar
  6. 6.
    Harrington K. Orthopedic surgical management of skeletal complications of malignancy. Cancer 1997;80: 1614–27.PubMedCrossRefGoogle Scholar
  7. 7.
    Harrington K, Sim F, Enis J, Johnson J, Dick H, Gristina A. Methylmethacrylate as an adjunct in internal fixation of pathological fractures: Experience with 375 cases. J Bone Joint Surg Am 1976;58:1047–55.PubMedGoogle Scholar
  8. 8.
    Wedin R, Bauer H, Wersäl P. Failures after operation for skeletal metastatic lesions of long bones. Clin Orthop 1999;358:128–39.PubMedGoogle Scholar
  9. 9.
    Janjan N. Radiation for bone metastasis. Cancer 1997;80:1628–44.PubMedCrossRefGoogle Scholar
  10. 10.
    Peltier L. Theoretical hazards in the treatment of pathological fractures by the kuntscher intramedullary nail. Surgery 1951;29:466–72.PubMedGoogle Scholar
  11. 11.
    Swanson K, Pritchard D, Sim F. Surgical treatment of metastasic disease of the femur. J Am Acad Orthop Surg 2000;8(1):56–65.PubMedGoogle Scholar
  12. 12.
    Lane J, Sculco T, Zolan S. Treatment of pathological fractures of the hip by endoprosthetic replacement. J Bone Joint Surg Am 1980;62:954–9.PubMedGoogle Scholar
  13. 13.
    Damron T, Sim F. Surgical treatment for metastatic disease of the pelvis and proximal end of the femur. ICL 2000;49:461–70.Google Scholar
  14. 14.
    Aaron A. Treatment of metastatic adenocarcinoma of the pelvis and the extremities -current concepts review. J Bone Joint Surg Am 1977;79:917–32.Google Scholar
  15. 15.
    Yazawa Y, Frassica F, Chao E, Pritchard D, Sim F, Shieves T. Metastasic bone disease: A study of the surgical treatment of 166 pathologic humeral and femoral fractures. Clin Orthop 1990;251:213–19.PubMedGoogle Scholar
  16. 16.
    Sperling J, Pritchard D, Morrey B. Total elbow arthroplasty following resection of tumors at the elbow. Clin Orthop 2000 (in press).Google Scholar
  17. 17.
    Lancaster J, Koman L, Gristina A. Pathologic fractures of the humerus. South Med J 1988; 81(1):52–5.PubMedCrossRefGoogle Scholar
  18. 18.
    Sim F, Pritchard D. Metastatic disease in the upper extremity. Clin Orthop 1982;169:83–94.PubMedGoogle Scholar
  19. 19.
    Allende BL. Lesiones metostésicas de huesos largos. Rev Asos Argent Ortop Traumetol 2003;67(3):161–5.Google Scholar

Copyright information

© Springer-Verlag London 2004

Authors and Affiliations

  • B. T. Allende
  • B. L. Allende

There are no affiliations available

Personalised recommendations