Wound Healing: Potential Therapeutic Modulation

  • W. H. Akeson
  • A. Giurea


Injury invokes a vigorous healing response in soft tissue as it does in bone. The needs of individual survival undoubtedly required such an evolutionary response as a survival mechanism. Inevitably the control mechanisms of the healing response will not infrequently extend beyond the range of the ideal. When the response to soft tissue injury is excessively exuberant, complications are encountered such as keloid formation, peritoneal adhesion, intestinal stricture, tendon adhesion, epidural fibrosis, and arthrofibrosis with attendant joint contractures, to name just a few. An important case in point is the loss of range of motion which occurs occasionally after knee injuries or knee surgery in spite of seemingly appropriate initial management and subsequent rehabilitation.


Anterior Cruciate Ligament Wound Repair Fetal Healing Epidural Fibrosis Fetal Wound 
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Copyright information

© Springer-Verlag London 2004

Authors and Affiliations

  • W. H. Akeson
  • A. Giurea

There are no affiliations available

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