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Introduction

  • Colin G. Miller
  • Derek Pearson
Chapter

Abstract

There have been many books published about the design, conduct and analysis of clinical trials. Why are osteoporosis trials a special case deserving a book of their own? There are three main reasons. Firstly, most diseases have a well-understood definition and etiology. Osteoporosis is a disease that is understood by those working in it, but currently has no definition that is agreeable across the medical and scientific community and a poorly understood etiology. It is within this framework that the pharmaceutical industry is trying to develop new treatments for the so-called “silent epidemic”.

Keywords

Bone Mineral Density Fracture Risk Bone Mineral Density Measurement Proven Treatment International Osteoporosis Foundation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    National Institutes of Health Consensus Development Conference Statement: Osteoporosis Prevention, Diagnosis, and Therapy March 27–29, 2000 ( http://odp.od.nih.gov/consensus/cons/111/111 _statement.pdf).
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    Assessment of Fracture Risk and its Application to Screening for Postmenopausal Osteoporosis. Report of a WHO Study Group. Geneva: World Health Organization. 1994Google Scholar
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Copyright information

© Springer-Verlag London 2002

Authors and Affiliations

  • Colin G. Miller
  • Derek Pearson

There are no affiliations available

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