Abstract
Morson and Dawson (1990)1 define an intestinal polyp as a mucosal projection into the lumen of the bowel. This does not indicate the underlying nature of the lesion. The polyps can be single or multiple and if multiple they may be in small numbers or in hundreds or thousands — polyposis. Different types of polyp are produced by different pathological processes: neoplasia leads to adenoma, inflammation to an inflammatory polyp, malformation leads to juvenile and Peutz—Jeghers polyps and dysmaturation to the hyperplastic (metaplastic) polyp. The gross and microscopic features of these different types are beautifully illustrated in Morson’s colour atlas (1988)2.
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References
Morson BC, Dawson IMP (1990) Gastrointestinal pathology, 3rd edn. Blackwell Scientific, Oxford
Morson BC (1988) Colour atlas of gastrointestinal pathology. Oxford University Press, Oxford
Konishi F, Morson BC (1982) Pathology of colorectal adenomas. J Clin Pathol 35: 830–841
Williams AR, Balasooriya BAW, Day DW (1982) Polyps and cancer of the large intestine. Necropsy study in Liverpool. Gut 23: 835–842
Vatn MH, Stalsberg H (1982) The prevalence of polyps of the large intestine in Oslo: an autopsy study. Cancer 49: 819–825
Gerhartz CD, Gabbert H, Krummel F (1987) Age-dependent shift to the right in the localisation of colorectal adenomas. Virchows Arch [A] 411: 591–598.
Bernstein MA, Feczko PJ, Halpert RD, Simms SM, Ackerman LV (1985) Distribution of colonic polyps. Increased incidence of proximal lesions in older patient. Radiology 155: 35–38
Correa P (1978) Epidemiology of polyps and cancer. In: The pathogenesis of colorectal cancer. B.C. Morson (ed). Saunders, Philadelphia, pp 126–152
Morson BC, Bussey HJR (1985) Magnitude of risk for cancer in patients with colorectal adenomas. Br J Surg 72: 523–528
Lovatt E (1976) Family studies in cancer of the colon and rectum. Br J Surg 63: 13–18
Hill MJ, Morson BC, Bussey HJR (1977) Aetiology of adenoma—carcinoma sequence in large bowel. Lancet i: 535–538
Burt RW, Bishop DT, Cannon LA, Dowdle MA, Lee RG, Skolnick MH (1985) Dominant inheritance of adenomatous colonic polyps and colorectal cancer. N Engl J Med 312: 1540–1544
Morson BC, Sobin LH (1976) International histological classification of tumours, No. 15. Histological typing of intestinal tumours. World Health Organization, Geneva
Muto T, Bussey HJR, Morson BC (1975) The evolution of cancer of the colon and rectum. Cancer 36: 2251–2263
Wolff WI, Shinya H (1975) Definitive treatment of “malignant” polyps of the colon. Ann Surg 182: 516–525
Muto T, Kamiya J, Sawada T et al. (1985) Small “flat adenoma” of the large bowel with special reference to its cinicopathologic features Dis Colon Rectum 28: 847–851
Day DW (1984) The adenoma—carcinoma sequence. Scand J Gastroenterol 19 (Suppl 104): 99–108
Grinnell RS, Lane N (1958) Benign and malignant adenomatous polyps and papillary adenomas of the colon and rectum. An analysis of 1856 tumours in 1335 patients. Surg Gynecol Obstet 106: 519–538
Brown LJR, Smeeton NC, Dixon MF (1985) Assessment of dysplasia in colorectal adenomas: an observer variation and morphometric study. J Clin Pathol 38: 174–179
Goh HS, Jass JR (1986) DNA content and the adenoma—carcinoma sequence in the colorectum. J Clin Pathol 39: 387–392
Morson BC, Bussey HJR, Samoorian S (1977) Policy of local excision for early cancer of the colon and rectum. Gut 18: 1045–1050
Cooper HS (1983) Surgical pathology of endoscopically removed malignant polyps of the colon and rectum. Am J Surg Pathol 7: 613–623
Muto T, Konishi F, Sawada T et al. (1987) Colonoscopic polypectomy as a tool for management of colonic polyps and detection of new lesions. Ann Acad Med Singapore 16: 427–431
Sawada T, Hojo K, Moriya Y (1989) Colonoscopic management of focal and early colorectal carcinoma. Baillière Clin Gastroenterol Colorectal Cancer 3: 627–645
Bussey HJR (1975) Familial polyposis coli. Johns Hopkins University Press, Baltimore.
Peutz JLA (1921) On a very remarkable case of familial polyposis of the mucous membrane of the intestinal tract and nasopharynx accompanied by peculiar pigmentations of the skin and mucous membrane. Ned Tijdschr Geneeskd 10: 134–146
Jeghers H (1944) Pigmentation of the skin. N Engl J Med 231: 88
Bartholomew LG, Dahlin D, Waugh JM (1957) Intestinal polyposis associated with mucocutaneous melanin pigmentation ( Peutz—Jeghers syndrome ). Gastroenterology 32: 434–451
Giardiello FM, Welsh SB, Hamilton SR et al. (1987) Increased risk of cancer in Peutz —Jeghers syndrome. N Engl J Med 316: 1511–1514
Dozois RR, Judd ES, Dahlin DC, Bartholomew LG (1969) The Peutz—Jeghers syndrome: is there a predisposition to the development of intestinal malignancy? Arch Surg 98: 509–516
Shepherd NA, Bussey HJR, Jass JR (1987) Epithelial misplacement in Peutz—Jeghers polyps: a diagnostic pitfall. Am J Surg Pathol 11: 743–749
Spigelman AD, Murday V, Phillips RKS (1989) Cancer and the Peutz—Jeghers syndrome. Gut 30: 1588–1590
Horrilleno EG, Eckert C, Ackerman LV (1957) Polyps of the rectum and colon in children. Cancer 10: 1210–1220
Knox WG, Miller RE, Begg CF, Zintel HA (1960) Juvenile polyps of the colon: a clinicopathologic analysis of 75 polyps in 43 patients. Surgery 48: 201–210
McColl I, Bussey HJR, Veale AM, Morson BC (1964) Juvenile polyposis coli. Proc R Soc Med 57: 896–897
Bussey HJR (1970) Gastrointestinal polyposis. Gut 11: 970–978
Bartpik W, Botruk E, Ryzko J, Rondio H, Rasinski A, Orlowska J (1986) Short-and long-term results of colonic polypectomy in children. Gastrointest Endosc 32: 389–392
Perisic VN (1987) Colorectal polyps: an important cause of rectal bleeding. Arch Dis Child 62: 188–203
Jarvinen H, Franssila KO (1984) Familial juvenile polyposis coli: increased risk of colorectal cancer. Gut 25: 792–800
Morson BC (1962) Some peculiarities in the histology of intestinal polyps. Dis Colon Rectum 5: 337–344
Williams GT, Arthur JF, Bussey HJR, Morson BC (1980) Metaplastic polyps and polyposis of the colorectum. Histopathology 4: 115–170
Stemmermann GN, Yatani R (1973) Diverticulosis and polyps of the large intestine. A necropsy study of Hawaii Japanese. Cancer 31: 1260–1270
Eide TJ (1986) Prevalence and morphological features of adenomas of the large intestine in individuals with and without colorectal carcinoma. Histopathology 10: 111–118
Cooper HS, Patchchefsky AS, Marks G (1979) Adenomatous and carcinomatous changes within hyperplastic colonic epithelium. Dis Colon Rectum 22: 152–156
Bengoachea O, Martinez-Penuela TM, Larrinaju B, Valendi J, Borda F (1987) Hyperplastic polyposis of the colorectum and adenocarcinoma in a 24-year-old man. Am J Surg Pathol 11: 323–327
Waye JD (1988) Hyperplastic colon polyps — are they markers? Ann Intern Med 109: 851–852
Dukes CE (1954) The surgical pathology of ulcerative colitis. Ann R Coll Surg Engl 14: 389–400
Edling NP, Eklöf O (1961) Radiological findings and prognosis in ulcerative colitis. Acta Chir Scand 121: 299–308
Kelly JK, Langevin JM, Price LM, Marshfield VB, Share S, Blustein P (1986) Giant and symptomatic inflammatory polyps of the colon in idiopathic inflammatory bowel disease. Am J Surg Pathol 10: 420–428
Kaplan B, Benson J, Rothstein F, Dahms B, Halpin T (1984) Lymphonodular hyperplasia of the colon as a pathologic finding in children with lower gastrointestinal bleeding. J Pediatr Gastroenterol Nutr 3: 704–708
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© 1993 Springer-Verlag London Limited
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Schofield, P.F., Haboubi, N.Y., Martin, D.F. (1993). Benign Epithelial Tumours and Polyps. In: Highlights in Coloproctology. Springer, London. https://doi.org/10.1007/978-1-4471-3456-5_11
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DOI: https://doi.org/10.1007/978-1-4471-3456-5_11
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