Summary
Wound debridement, the removal of devitalised and contaminated tissue, is an essential phase in the treatment of ulcers. In some cases surgical debridement is not the treatment of choice. Several types of enzymes can be used in wound debridement. We investigated a new enzymatic preparation containing endo- and exopeptidases derived from Antarctic krill. In an observer-blind study 31 venous leg ulcers were treated either with krill enzyme or with a routine non-enzymatic treatment. The enzymatic treatment was significantly better than the control treatment (p 0.001). A newly developed method (computer image analysis) was used to evaluate the process of wound debridement.
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© 1990 Springer-Verlag London Limited
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Westerhof, W., Mekkes, J.R. (1990). Krill and Other Enzymes in Enzymatic Wound Debridement. In: Wadström, T., Eliasson, I., Holder, I., Ljungh, Å. (eds) Pathogenesis of Wound and Biomaterial-Associated Infections. Springer, London. https://doi.org/10.1007/978-1-4471-3454-1_23
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DOI: https://doi.org/10.1007/978-1-4471-3454-1_23
Publisher Name: Springer, London
Print ISBN: 978-3-540-19596-2
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