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Interactions of 4-Quinolones with Other Agents — The Importance in Assessing Practical Antibacterial Potency

  • C. S. Lewin
  • J. T. Smith
Part of the Springer Series in Applied Biology book series (SSAPPL.BIOLOGY)

Abstract

The 4-quinolones are broad spectrum antibacterials and therefore are generally used as single antimicrobial agents. However, in certain situations, they can be combined with a second antibacterial to provide better anti-staphylococcal and anti-streptococcal activity. For example, when empirically treating febrile episodes in immunocompromised patients (Smith et al. 1988). Furthermore, it has been suggested that the 4-quinolones should be used in conjunction with a second antibacterial in order to prevent the emergence of 4-quinolone-resistant organisms during therapy (Scully et al. 1986; Farrag et al. 1986).

Keywords

Minimum Inhibitory Concentration Nutrient Broth Nalidixic Acid Antimicrob Agent Neutropenic Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag London Limited 1990

Authors and Affiliations

  • C. S. Lewin
  • J. T. Smith

There are no affiliations available

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