Anaerobiosis and Staphylococcal Resistance to Certain 4-Quinolones

  • D. J. C. Knowles
  • G. T. Grimes
  • L. S. Holmes
Part of the Springer Series in Applied Biology book series (SSAPPL.BIOLOGY)


Many of the fluorinated 4-quinolones are very potent antibacterial agents acting on the same target, DNA Gyrase, as nalidixic acidl. Unlike nalidixic acid and the older compounds, their level of activity is such as to include a broad range of both Gram negative and Gram positive bacteria.


Anti Bacterial Agent Nalidixic Acid Differential Susceptibility Oxolinic Acid Pipemidic Acid 
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Copyright information

© Springer-Verlag London Limited 1990

Authors and Affiliations

  • D. J. C. Knowles
  • G. T. Grimes
  • L. S. Holmes

There are no affiliations available

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