The Premenstrual Syndrome

  • Isabel Stabile
  • Tim Chard
  • Gedis Grudzinskas

Abstract

The premenstrual syndrome is a complex of physical and psychological symptoms of unknown aetiology, not associated with organic disease, which recur regularly during the same phase of each ovarian cycle and then regress. Ovulation but not menstruation is essential to the diagnosis. The type of symptoms (physical, e.g., oedema, weight gain, bloating and breast tenderness, and psychological, e.g., irritability, tiredness, depression), but not their severity remain constant from one cycle to the next. The diagnosis is usually based on history and self-assessment questionnaires. The prevalence ranges from 20% to 40% of the population.

Keywords

Placebo Depression Progesterone Oestradiol Pyridoxine 

Copyright information

© Springer-Verlag London Limited 1996

Authors and Affiliations

  • Isabel Stabile
    • 1
  • Tim Chard
    • 2
  • Gedis Grudzinskas
    • 3
  1. 1.Center for Prevention and Early Intervention PolicyThe Florida State UniversityTallahasseeUSA
  2. 2.Department of Obstetrics, Gynaecology and Reproductive PhysiologySt. Bartholomew’s Hospital Medical CollegeLondonUK
  3. 3.Academic Unit of Obstetrics and GynaecologyThe Royal London HospitalLondonUK

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