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Vertigo: Its Multisensory Syndromes pp 215–228Cite as

Drugs and Vertigo

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Part of the book series: Clinical Medicine and the Nervous System ((CLIN.MED.NERV.))

Abstract

The list of drugs which may have adverse effects on hearing or balance is impressive. It includes anaesthetic agents, anticonvulsants, antidepressants, analgesics, antidiabetic agents, antihypertensive agents, anti-inflammatory drugs, contraceptives, cytotoxic agents, cardiovascular drugs, sedatives, and tranquilhsers (Table 21.1; Ballantyne and Ajodhia 1984). There is no common syndrome or mechanism of drug vertigo. The spectrum covers all kinds of side effects. Beta-blockers may induce bradycardia with unspecific drowsiness or dizziness (Cruickshank 1981). More severe side effects include hypoglycaemia (Harrill 1951; Currier 1970), positional alcohol nystagmus/vertigo (p. 154), cerebellar ataxia and oculomotor dysfunction in acute diphenylhydantoine intoxication (Nozue et al. 1973), and bilateral vestibular loss with oscillopsia and unsteadiness of gait due to gentamicin toxicity (Ramsden and Ackrill 1982). Drug induced patterns of pathological eye movements include positional, downbeat, and gaze-evoked nystagmus and preferably reflect transient flocculus dysfunction (Esser and Brandt 1983).

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Authors and Affiliations

  1. Klinikum Grosshadern, Ludwig-Maximilians-Universität München, Marchioninistrasse 15, 8000, München 70, Germany

    Thomas Brandt (Professor of Neurology, Director Neurologische Klinik)

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© 1991 Springer-Verlag London Limited

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Brandt, T. (1991). Drugs and Vertigo. In: Vertigo: Its Multisensory Syndromes. Clinical Medicine and the Nervous System. Springer, London. https://doi.org/10.1007/978-1-4471-3342-1_21

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  • DOI: https://doi.org/10.1007/978-1-4471-3342-1_21

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3344-5

  • Online ISBN: 978-1-4471-3342-1

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