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Diseases of the Kidney and Lower Urinary Tract

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Abstract

The kidneys develop from an intermediate mass of mesoderm (the nephrogenic cord) situated on the posterior wall of the intraembryonic coelom between the dorsal somites and the lateral plate mesoderm. Three successive excretory organs develop in the early human embryo—the pronephros, the mesonephros and the metanephros. These three “kidneys” form sequentially and progressively and more caudally, but there is considerable overlap both chronologically and topographically. The pronephros and mesonephros are transient vestigial structures, and the definitive kidney forms from the metanephros. The mesonephric (or Wolffian) duct persists in male embryos as the duct of the epididymis, the vas deferens, and the ejaculatory duct.

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Risdon, R.A. (1989). Diseases of the Kidney and Lower Urinary Tract. In: Berry, C.L. (eds) Paediatric Pathology. Springer, London. https://doi.org/10.1007/978-1-4471-3337-7_8

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