The pinna and external auditory meatus are removed surgically mainly for the treatment of malignant neoplasms; the mastoid bone, the air cells, the malleus and the incus are usually removed for drainage of chronic suppurative otitis media while the stapes is removed for otosclerosis. Examination of this surgical material allows a study of only a few pathological processes. In order to study adequately the deeper part of the ear canal, the whole middle ear and the inner ear, it is necessary to deal with material taken at autopsy. For this purpose the whole temporal bone should be removed as one block.
KeywordsFormaldehyde Polysaccharide Drilling Dehydration Paraffin
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- Anson BJ, Donaldson JA (1981) Surgical anatomy of the temporal bone, 3rd edn. WB Saunders, PhiladelphiaGoogle Scholar
- Baker RD (1967) Post mortem examination. Specific methods and procedures. WB Saunders, PhiladelphiaGoogle Scholar
- Bloom W, Fawcett DW (1968) A textbook of histology, 9th edn. WB Saunders, Philadelphia, pp 814–815Google Scholar
- Friedmann I, Ballantyne J (1984) Ultrastructural atlas of the inner ear. Butterworth, LondonGoogle Scholar
- Graham MD, Reams C, Perkins R (1978) Human tympanic membrane - malleus attachment. Preliminary study. Ann Otol Rhinol Laryngol 87: 426–431Google Scholar
- Iurato S, Bredberg G, Bock G (1982) Functional histopathology of the human audio-vestibular organ. Euro-data hearing project. Commission of the European Communities.Google Scholar
- Karnovsky MJ (1965) A formaldehyde-glutaraldehyde fixative of high osmolality for use in electron microscopy. J Cell Biol 27: 137A - 138AGoogle Scholar
- Perry ET (1957) The human ear canal. Charles C Thomas,Springfield IllGoogle Scholar
- Phelps PD, Lloyd GAS (1983) Radiology of the ear. Blackwell Scientific, OxfordGoogle Scholar
- Sadé J (1966) Middle ear mucosa. Arch Otolaryngol 84:137–143 Schuknecht HF ( 1974 ) Pathology of the ear. Harvard University Press, Cambridge MassGoogle Scholar