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Applied Radiobiology

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The Radiotherapy of Malignant Disease

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Abstract

The most satisfactory therapeutic regimens for local tumour control have been derived empirically,but the empiricism fails to explain why the best available regimens do not succeed in every case. Not only does empiricism fail to explain failures, it also fails to explain successes. Radiobiological explanations of treatment failure offer, in principle, suggestions for the design of novel regimes of radiotherapy, alone or in combination with other physical and chemical agents, which may reduce the incidence of treatment failures. This is the “predictive” role of radiobiology as opposed to its “interpretive” role. To date, benefits of predictive radiobiology have not been striking, leading to the attitude that radiobiology is an expensive irrelevance.

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Further Reading

  • Hahn GM (1982) Hyperthermia and cancer. Plenum Press, New York.

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  • Adams GE (1977) Hypoxic cell sensitisers for radiotherapy. In: Becker FF (ed) Cancer, vol 6, p 181. Plenum, New York

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General Radiobiology for the Radiotherapist

  • Hall EJ (1978) Radiobiology for the radiologist. Harper and Row, New York

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The Radiobiology of Tissues

  • Selected chapters in: Potten CS, Hendry JH (eds) (1983) Cytotoxic insult to tissues: effects on cell lineages. Churchill Livingstone, Edinburgh

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Tumours

  • Kallman.RF, Rockwell,S (1977): Effects of radiationon animal tumour models. In: Becker FF (ed) Cancer, vol 6, p 225. Plenum, New York

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New Treatments

  • Catterall M, Bewley DK (1979) Fast neutrons in the treatment of cancer. Academic Press, and Grune and Stratton, New York

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Authors
  1. M. L. Sutton
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  2. J. H. Hendry
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Editor information

Editors and Affiliations

  1. University of Manchester, UK

    Eric C. Easson CBE, MSc, MD, FRCP, FRCR (Late Emeritus Professor of Radiotherapy, formerly Director of Radiotherapy) (Late Emeritus Professor of Radiotherapy, formerly Director of Radiotherapy)

  2. Christie Hospital and Holt Radium Institute, Manchester, UK

    Eric C. Easson CBE, MSc, MD, FRCP, FRCR (Late Emeritus Professor of Radiotherapy, formerly Director of Radiotherapy) & R. C. S. Pointon MA, FRCP, FRCR (Director of Radiotherapy) (Late Emeritus Professor of Radiotherapy, formerly Director of Radiotherapy) &  (Director of Radiotherapy)

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© 1985 Springer-Verlag Berlin Heidelberg

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Sutton, M.L., Hendry, J.H. (1985). Applied Radiobiology. In: Easson, E.C., Pointon, R.C.S. (eds) The Radiotherapy of Malignant Disease. Springer, London. https://doi.org/10.1007/978-1-4471-3322-3_2

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  • DOI: https://doi.org/10.1007/978-1-4471-3322-3_2

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3324-7

  • Online ISBN: 978-1-4471-3322-3

  • eBook Packages: Springer Book Archive

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