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Abstract

Five elements are involved in the act of making a histopathological diagnosis. First, the patient who contributes the tissue and about whom biochemical, radiological, immunological, and other clinical data may be available. Secondly, the tissue itself and the histological section, a two-dimensional artifact of a three-dimensional object. Thirdly, the microscope as a diagnostic tool. Fourthly, our bank of knowledge of morphological changes in disease processes against which the tissue biopsy is assessed. And lastly, the psychology of perception, the mechanism by which the observer recognises pathological changes in the tissue.

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© 1981 Springer-Verlag Berlin Heidelberg

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Underwood, J.C.E. (1981). Interpretation of Histological Appearances. In: Introduction to Biopsy Interpretation and Surgical Pathology. Springer, London. https://doi.org/10.1007/978-1-4471-3301-8_4

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  • DOI: https://doi.org/10.1007/978-1-4471-3301-8_4

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3303-2

  • Online ISBN: 978-1-4471-3301-8

  • eBook Packages: Springer Book Archive

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