Abstract
This paper presents data supporting the model that classical seminoma originates from a primordial germ cell/gonocyte in which maturation is blocked. Although spermatocytic seminoma might also originate from an embryonic germ cell, it retains the capacity to undergo further maturation, including partial meiosis. Moreover, we identified immunohistochemical markers helpful in the diagnosis of spermatocytic seminomas.
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Looijenga, L.H.J., Stoop, H., van Gurp, R.J.H.L.M., de Krijger, R., Oosterhuis, J.W. (2002). Reactivity of Germ Cell Maturation Stage-specific Markers in Classical and Spermatocytic Seminoma. In: Harnden, P., Joffe, J.K., Jones, W.G. (eds) Germ Cell Tumours V. Springer, London. https://doi.org/10.1007/978-1-4471-3281-3_6
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DOI: https://doi.org/10.1007/978-1-4471-3281-3_6
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