Introducing the Measurement of Quality of Life into Clinical Practice: Technology and Mechanisms

  • R. Sanders
  • G. Velikova
  • A. Smith
  • D. Stark
  • E. P. Wright
  • J. Randerson Moor
  • D. T. Bishop
  • P. Selby
Conference paper


Health-related quality of life (QL) is a recognised and important patient-related outcome of anti-cancer treatment, which can be measured by carefully developed, psychometrically robust, questionnaires. Although the validity and sensitivity of the cancer QL questionnaires is now widely accepted and they are frequently used in therapeutic clinical trials, they have yet to impact fully on patients’ care and are little used by practising oncologists. Several barriers have hampered the practical use of QL measures for individual patients, including the logistic barrier of collection and analysis of large amounts of data, the conceptual barrier of determining the clinical meaning of QL scores, the theoretical concerns over whether instruments developed for group comparisons can be used for individual patients, and the lack of research data on the possible benefits for individual patients. Thus, whilst oncology professionals are broadly convinced of the value of the concept and measurement of QL and its utilisation in clinical trials is increasing, its impact on routine clinical practice remains small.


Panic Disorder Touch Screen Generalise Anxiety Disorder Serotonin Transporter Gene Phobic Disorder 
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Copyright information

© Springer-Verlag London Limited 2002

Authors and Affiliations

  • R. Sanders
    • 1
  • G. Velikova
    • 1
  • A. Smith
    • 1
  • D. Stark
    • 1
  • E. P. Wright
    • 1
  • J. Randerson Moor
    • 1
  • D. T. Bishop
    • 1
  • P. Selby
    • 1
  1. 1.Imperial Cancer Research Fund Clinical Centre in LeedsCancer Research Building St James’s University HospitalLeedsUK

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