Organ Sparing Tumour Resection in Testicular Germ Cell Tumours (TGCT) — Long-term Follow-up

Abstract

Synchronous and metachronous bilateral TGCT occur in 2 to 5 per cent of patients. Bilateral radical orchiectomy has been the standard treatment resulting not only in infertility, but also in life-long dependency on exogenous testosterone substitution and major psychological disturbances due to bilateral castration at young age. Therefore, organ-sparing surgery has been proposed in small series of patients with either bilateral testis cancer or TGCT developing in a solitary testicle [1–3]. The aim of the current study was to evaluate the indications, surgical technique and outcome of organ preserving tumour enucleation rather than standard orchiectomy in patients with bilateral TGCTs or TGCT in a solitary testicle. We present the long term data of 73 patients included in our protocol.