Skip to main content

Radiosurgical Treatment of Bone Metastasis of the Limbs

  • Chapter
Bone Metastases
  • 149 Accesses

Abstract

Bone metastases occur less frequently in the limbs than in the spine and pelvis. Metastases of the limbs are mainly found in the femur and humerus. The primary tumours from which they derive are: breast (30%), prostate (16%), lung (12%), kidney (10%), digestive system (6%) and thyroid (3%). In about 20% of cases, the origin of the primary tumour remains unknown. Bone metastases cause major discomfort because of the disability associated with fractures and/or pain. Survival should be assessed according to both disease progression and performance status, using the Karnofski score. Patients with a short survival time (2 weeks) require palliative treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Arcangeli G, Micheli A, Arcangeli G et al (1989) The responsiveness of bone metastases to radio-therapy: the effect of site, histology and radiation dose on pain relief. Radiother Oncol 14:95–101.

    Article  PubMed  CAS  Google Scholar 

  • Blitzer PH (1985) Reanalysis of the RTOG study of the palliation of symptomatic osseous metastases. Cancer 55: 1468–1472.

    Article  PubMed  CAS  Google Scholar 

  • Cheng DS, Seitz CB, Eyre HJ (1980) Nonoperative management of femoral, humeral, and acetabular metastases in patients with breast carcinoma. Cancer 45: 1533–1537.

    Article  PubMed  CAS  Google Scholar 

  • Cole DJ (1989) A randomized trial of single treatment versus conventional fractionation in the palliative radiotherapy of painful bone metastases. Clin Oncol 1: 59–62.

    Article  CAS  Google Scholar 

  • Nielsen OS, Munro AJ, Tannock IF (1991) Bone metastases: pathophysiology and management policy. J Clin Oncol 9 (3): 509–524.

    PubMed  CAS  Google Scholar 

  • Price P, Hoskin PJ, Austin A et al (1986). Prospective randomized trial of single and multifraction radiotherapy schedules in the treatment of painful bone metastases. Radiother Oncol 6:247–255.

    Article  PubMed  CAS  Google Scholar 

  • Tong D, Gillick L, Ilendrickson FR (1982) The palliation of symptomatic osseous metastases. Final results of the study by the Radiation Therapy Oncology Group. Cancer 50:893–899.

    Article  PubMed  CAS  Google Scholar 

Further Reading

  • Bates T (1989) Radiotherapy for bone metastases. Clin Oncol 1: 57–58.

    Article  CAS  Google Scholar 

  • Berrettoni BA, Carter JR (1986) Mechanisms of cancer metastases. J Bone Joint Surg 68: 308–312.

    PubMed  CAS  Google Scholar 

  • Carter RL (1985) Patterns and mechanisms of localized bone by tumours: studies with squamous carcinomas of the head and neck. Crit Rev Clin Lab Sci 22: 275–315.

    Article  PubMed  CAS  Google Scholar 

  • Carter RL (1985) Patterns and mechanisms of bone metastases. J Royal Soc Med 78: 2–6.

    Google Scholar 

  • Fidler IJ, Radinsky R (1990) Genetic control of cancer metastases. J Natl Cancer Inst 82: 166–168.

    Article  PubMed  CAS  Google Scholar 

  • Hoskin PJ (1988) Scientific and clinical aspects of radiotherapy in the relief of bone pain. Cancer Sury 7: 69–86.

    CAS  Google Scholar 

  • Liotta LA, Steller Stevenson WG (1989) Principles of molecular cell biology of cancer; cancer metastases. In: De Vita VT, Hellman S, Rosenberg SA (eds) Cancer: principles and practice of oncology. JB Lippincott, Philadelphia, pp 98–115.

    Google Scholar 

  • Lote K, Walloc A, Bjersand A (1986) Bone metastasis. Prognosis, diagnosis and treatment. Acta Radiol Oncol 25: 227–232.

    Article  PubMed  CAS  Google Scholar 

  • Malawel MM, Delaney TF (1989) Treatment of mestastasis cancer to bone. In: De Vita VT, Hellman S, Rosenberg SA (eds) Cancer: principles and practice of oncology. JB Lippincott, Philadelphia, pp 2298–2317.

    Google Scholar 

  • Mauch PM, Drew MA (1985) Treatment of metastatic cancer to bone. In: De Vita VT, Hellman S, Rosenberg SA (eds) Cancer: principles and practice of oncology. JB Lippincott, Philadelphia, pp 2132–2141.

    Google Scholar 

  • Paterson AHG (1987) Bone metastasis in breast cancer, prostate cancer and myeloma. Bone 8: 17–22 (suppl 1).

    Google Scholar 

  • Price P, Hoskin PJ, Easton D et al (1988) Low dose single fraction radiotherapy in the treatment of metastatic bone pain: a pilot study. Radiother Oncol 12: 297–300.

    Article  PubMed  CAS  Google Scholar 

  • Salazar OM, Rubin P, Hendrickson FR et al (1986) Single dose half-body irradiation for the palliation of multiple bone metastases from solid tumours. Int J Radiation Oncol Biol Phys 7: 773–781.

    Article  Google Scholar 

  • Wagnor G (1984) Frequency of pain in patients with cancer. Recent Results Cancer Res 89: 64–71.

    Article  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag London

About this chapter

Cite this chapter

Pignon, T., Juin, P., Glard, Y., Poitout, D.G. (2002). Radiosurgical Treatment of Bone Metastasis of the Limbs. In: Poitout, D.G. (eds) Bone Metastases. Springer, London. https://doi.org/10.1007/978-1-4471-3251-6_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-3251-6_9

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3253-0

  • Online ISBN: 978-1-4471-3251-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics