Treatment of Secondary Spinal Tumours

  • C. S. B. Galasko
  • J. B. Spilsbury


The diagnosis and treatment of spinal metastatic tumours is an increasing part of an orthopaedic spinal surgeon’s role, as the life expectancy of patients with treatable malignancy increases.


Skeletal Metastasis Spinal Metastasis Anterior Column Posterior Stabilisation Spinal Instability 
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  1. Bridwell KH, Jenny AB, Saul T et al (1988) Posterior segmental spinal instrumentation (PSSI) with posterolateral decompression and debulking for metastatic thoracic and lumbar spine disease: limitations of the technique. Spine 13: 1383–1394.PubMedCrossRefGoogle Scholar
  2. Brihaye J, Ectors P, Lemort M et al (1988) The management of spinal epidural metastases. Adv Tech Stand Neurosurg 16: 121.PubMedCrossRefGoogle Scholar
  3. Constans JP, de Divitiis E, Donzelli R et al (1983) Spinal metastases with neurological manifestations. Review of 600 cases. J Neurosurg 59: 111–118.PubMedCrossRefGoogle Scholar
  4. Cotten A, Dewatre F, Cortet B et al (1996) Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up. Radiology 200: 525–530.PubMedGoogle Scholar
  5. Cunin G, Boissonnett H, Petite H et al (2000) Experimental vertebroplasty using osteoconductive granular material. Spine 25: 1070–1076.PubMedCrossRefGoogle Scholar
  6. Cybulski GR (1989) Methods of surgical stabilisation of metastatic disease of the spine. Neurosurgery 25: 240–252.PubMedCrossRefGoogle Scholar
  7. De Wald RL, Bridwell KH, Prodromas C et al (1985) Reconstructive spinal surgery as palliation of metastatic malignancies of the spine. Spine 10 (1): 21–26.CrossRefGoogle Scholar
  8. Einhorn TA (2000) Vertebroplasty: an opportunity to do something really good for patients. Spine 25: 1051–1052.PubMedCrossRefGoogle Scholar
  9. Fidler MW (1987) Pathological fractures of the spine including those causing anterior spinal cord compression: surgical management. In: Galasko CSB, Noble J (eds) Recent developments in orthopaedic surgery; Festschrift to Sir Harry Platt. Manchester University Press, Manchester, pp 94–103.Google Scholar
  10. Fidler MW (1994) Radical resection of vertebral body tumours: a surgical technique used in ten cases. J Bone Joint Surg Br 76: 765–772.PubMedGoogle Scholar
  11. Flatley TJ, Anderson MH, Anast GY (1984) Spinal instability due to malignant disease: treatment by segmental spinal stabilisation. J Bone Joint Surg Am 66: 47–52.PubMedGoogle Scholar
  12. Galasko CSB (1986) Skeletal metastases. Butterworth, London.Google Scholar
  13. Galasko CSB (1991) Spinal instability secondary to metastatic cancer. J Bone Joint Surg Br 73: 104–108.PubMedGoogle Scholar
  14. Galasko CSB, Norris HE, Crank S (2000) Spinal instability secondary to metastatic cancer. J Bone Joint Surg 82A: 570–576.PubMedGoogle Scholar
  15. Galasko CSB, Sylvester BS (1978) Back pain in patients treated for malignant tumours. Clin Oncol 4: 273–283.PubMedGoogle Scholar
  16. Harrington KD (1981) The use of methylmethacrylate for vertebral-body replacement and anterior stabilization of pathological fracture-dislocations of the spine due to metastatic malignant disease. J Bone Joint Surg 63A (1): 36–46.PubMedGoogle Scholar
  17. Hertlein H, Mittlmeier T, Piltz S et al (1992) Spinal stabilisation for patients with metastatic lesions of the spine using a titanium spacer. Eur Spine J 1: 131–136.PubMedCrossRefGoogle Scholar
  18. Hodgson AR, Stock FF, Yang HS et al (1960) Anterior spinal fusion. The operative approach and pathological findings in 412 patients with Potts disease of the spine. Br J Surg 48: 172.PubMedCrossRefGoogle Scholar
  19. Hosono N,Yonenobu K, Fuji T et al (1995) Orthopaedic management of spinal metastases. Clin Orthop 312: 148–159.PubMedGoogle Scholar
  20. Johnson JR, Leatherman KD, Holt RT (1983) Anterior decompression of the spinal cord for neurological deficit. Spine 8: 396–405.PubMedCrossRefGoogle Scholar
  21. Kaneda K, Taneichi H, Abumi K et al (1997) Anterior decompression and stabilisation with the Kaneda device for thoraco-lumbar burst fractures associated with neurological deficits. J Bone Joint Surg Am 79A: 69–83.PubMedGoogle Scholar
  22. Lowery GL, Harms J (1997) Principles of load sharing. In: Bridwell KH, De Wald RL (eds) Textbook of spinal surgery, 2nd edn, ch 13. Lippincott-Raven, Philadelphia.Google Scholar
  23. McLain RF (1998) Endoscopically assisted compression of metastatic thoracic neoplasms. Spine 23: 113–235.Google Scholar
  24. O’Donoghue DS, Howell A, Walls J (1997) Orthopaedic management of structurally significant bone destruction in breast cancer bone metastasis. In the Proceedings of the British Orthopaedic Association. J Bone Joint Surg 79B (suppl 1): 98.Google Scholar
  25. Onimus M, Pappin P, Ganlough F (1996) Results of surgical treatment of spinal thoracic and lumbar metastasis. Eur Spine J 5: 407–411.PubMedCrossRefGoogle Scholar
  26. Schaberg J, Gainor BJ (1985) A profile of metastatic carcinoma of the spine. Spine 10: 19–20.PubMedCrossRefGoogle Scholar
  27. Tokuhashi Y, Matzaki H, Kawano H et al (1994) The indication of operative procedure for a metastatic spine tumor: a scoring system for the pre-operative evaluation of the prognosis. J Japan Orthopaed Assoc 68: 379–389.Google Scholar
  28. Weill A, Chiras J, Simon JM et al (1996) Spinal metastases: indications for and results of percutaneous injection of acrylic surgical cement. Radiol 199: 241–247.Google Scholar

Further Reading

  1. Belkoff SM, Mathis JM, Erbe EM et al (2000) Biomechanical evaluation of a new bone cement for use in vertebroplasty. Spine 25: 1061–1064.PubMedCrossRefGoogle Scholar
  2. Boxer BI, Todd CE, Coleman R et al (1989) Bone secondaries in breast cancer: the solitary metastasis. J Nucl Med 30: 1318.PubMedGoogle Scholar
  3. Findley GF (1984) Adverse effects of the management of spinal cord compression. J Neurol Neurosurg Psychiat 47: 761–768.CrossRefGoogle Scholar
  4. Galasko CSB (1996) Mechanisms of bone destruction in the development of skeletal metastasis. Nature 263 (5577): 507.CrossRefGoogle Scholar
  5. Gurr KE, McAffee PC, Shih CM (1988) Biomechanical analysis of anterior and posterior instrumentation systems after corpectomy. J Bone Joint Surg 70A: 1182.PubMedGoogle Scholar
  6. Kanayama M, Ng JT, Cunningham BW et al (1999) Biomechanical analysis of anterior versus circumferential spinal reconstruction for various anatomic stages of tumor lesions. Spine 24 (5): 445–450.PubMedCrossRefGoogle Scholar
  7. McLain RF, Sparling E, Benson DR (1993) Early failure of short segment pedicle instrumentation for thoraco lumbar fractures. J Bone Joint Surg 75: 162.PubMedGoogle Scholar

Copyright information

© Springer-Verlag London 2002

Authors and Affiliations

  • C. S. B. Galasko
  • J. B. Spilsbury

There are no affiliations available

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