The larynx is a relatively inaccessible organ, and the difficulties of reaching its inner surface during life, of inspecting it and sampling it for histological examination, have hampered the understanding of its disease processes. In the nineteenth century examination with a mirror—indirect laryngoscopy—was carried out with very great skill by the master laryngologists such as Sir Morell Mackenzie. Even biopsy was carried out by this means—a remarkable feat when it is recalled that topical anaesthesia by the use of cocaine was not introduced until 1884.
KeywordsFormaldehyde Lymphoma Adenocarcinoma Tuberculosis Cocaine
Unable to display preview. Download preview PDF.
- Kleinsasser O, translated by Stell PM (1979) Microlaryngoscopy and endolaryngeal microsurgery. Technique and typical findings, 2nd edn. University Park Press, BaltimoreGoogle Scholar