The larynx is a relatively inaccessible organ, and the difficulties of reaching its inner surface during life, of inspecting it and sampling it for histological examination, have hampered the understanding of its disease processes. In the nineteenth century examination with a mirror—indirect laryngoscopy—was carried out with very great skill by the master laryngologists such as Sir Morell Mackenzie. Even biopsy was carried out by this means—a remarkable feat when it is recalled that topical anaesthesia by the use of cocaine was not introduced until 1884.
KeywordsFreeze Section Vocal Cord Direct Laryngoscopy Pyogenic Granuloma Spindle Cell Carcinoma
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