Neutrophil CD11b Expression in Patients with Venous Disease
The white cell trapping hypothesis suggests that raised venous pressure causes white cell margination and activation, with the release of proteolytic enzymes and Superoxide radicals, believed responsible for the tissue destruction seen in chronic venous insufficiency . We have demonstrated raised levels of plasma lactoferrin  and elastase  as markers of neutrophil degranulation in patients with venous disease previously.
KeywordsMigration Superoxide Integrin
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