Abstract
Progress and improvements in preimplantation genetic testing historically have been driven by technological advance. Powerful new genetic technologies are being applied to PGT before their nuances or consequences are fully understood. The potential for discovering genome-wide information by techniques such as next generation sequencing raises particular practical, clinical and ethical problems not previously considered as part of preimplantation testing.
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DNA sequencing costs. Data from the NHGRI genome sequencing program (GSP). http://www.genome.gov/sequencingcosts/.
Fragouli E, Wells D. Aneuploidy in the human blastocyst. Cytogenet Genome Res. 2011;133:149–59.
Handyside A. PGD and aneuploidy screening for 24 chromosomes by genome-wide SNP analysis: seeing the wood and the trees. Reprod Biomed Online. 2011;23:686–91.
Human Fertilisation and Embryology Authority. Review of sex selection. 2002. http://www.hfea.gov.uk/517.html.
Julian S, Guy K. The moral obligation to create children with the best chance of the best life. Bioethics. 2009;23(5):274–90.
Sandel MJ. The case against perfection. The Atlantic Monthly. Apr 2004. http://jrichardstevens.com/articles/sandel-genetics.pdf.
Savulescu J. Procreative beneficence: why we should select the best children. Bioethics. 2001;15(5/6):413–26.
The Human Genome Project; Wellcome Trust Sanger Institute. http://www.sanger.ac.uk/about/history/hgp/
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Braude, P., Ogilvie, C.M. (2014). The Future of Preimplantation Genetic Testing: From Research Lab to Responsible Patient Care. In: El-Toukhy, T., Braude, P. (eds) Preimplantation Genetic Diagnosis in Clinical Practice. Springer, London. https://doi.org/10.1007/978-1-4471-2948-6_19
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DOI: https://doi.org/10.1007/978-1-4471-2948-6_19
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