Lymphohematopoietic Malignancies

  • Anneclaire J. De RoosEmail author
  • Parveen Bhatti


Lymphohematopoietic malignancies, which include lymphomas, leukemias, and multiple myeloma, encompass a heterogeneous, but related, group of cancers that, collectively, are among the top 5 or 6 most common cancers in women and men worldwide. The incidence rate increased dramatically during the latter half of the twentieth century in the USA, Europe, and other developed regions, and the causes of this dramatic increase remain unidentified. The lymphohematopoietic system appears to be vulnerable to neoplastic changes from a variety of occupational exposures. Accepted causes of lymphohematopoietic cancers are limited at this time to benzene, 1,3-butadiene, and ionizing radiation for myeloid cell leukemias. Probable causes for at least certain lymphohematopoietic cancer subtypes, that are as yet debated, are formaldehyde, ethylene oxide, certain pesticides, animal exposures, and trichloroethylene and other solvents.


Lymphoma Leukemia Benzene 1,3-Butadiene Ionizing radiation Formaldehyde Ethylene oxide Pesticides Animal exposures Trichloroethylene Solvents 


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Copyright information

© Springer-Verlag London 2014

Authors and Affiliations

  1. 1.Department of Occupational and Environmental HealthSchool of Public Health, Drexel UniversityPhiladelphiaUSA
  2. 2.Program in Epidemiology, Division of Public Health SciencesFred Hutchinson Cancer Research CenterSeattleUSA

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