Microbiological Diagnosis of Prosthetic Joint Infection

  • Jaime Esteban
  • Concepción Pérez-Jorge
  • Ramón Pérez-Tanoira
  • Enrique Gómez-Barrena


Diagnosis of Prosthetic Joint Infection is still a complex matter in clinical practice. Syndromic diagnosis includes the presence of several symptoms and signs together with the use of a combination of different techniques, including image analysis, biochemical markers and intraoperatory histopatology. Microbiological diagnosis is an essential part of this process, because it allows selection of the best possible antibiotic therapy, and even orients the surgical management and the potential outcome of the patient in some cases. Cultures of synovial fluids, periprosthetic tissues and implant sonication are the commonly recommended techniques, and a combination of these techniques allows reaching an etiologic diagnosis in most cases. However, rapid diagnosis is still a problem, because the lack of sensitivity and specificity of Gram stain of surgical products.


Cultures Imaging Aspiration Sonication 


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Copyright information

© Springer-Verlag London 2012

Authors and Affiliations

  • Jaime Esteban
    • 1
  • Concepción Pérez-Jorge
    • 1
  • Ramón Pérez-Tanoira
    • 1
  • Enrique Gómez-Barrena
    • 2
  1. 1.Bone and Joint Infection Unit, Department of Clinical MicrobiologyIIS-Fundación Jiménez DíazMadridSpain
  2. 2.Department of Orthopaedic Surgery and TraumatologyHospital “La Paz”MadridSpain

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