Abstract
This section covers acute and chronic cardio-respiratory complications of SCD including acute chest syndrome (ACS), and pulmonary hypertension (PHT). ACS is a common acute respiratory complication which is often misdiagnosed or delayed in diagnosis. ACS can rapidly progress to respiratory failure. There is a high risk of mortality if not diagnosed and treated appropriately. We describe the pathology, clinical features, diagnosis and management. Pulmonary hypertension (PHT) has recently emerged as a significant chronic complication with an increased risk of early mortality. In this section we have attempted to give an up-to-date account of PHT in sickle cell disease, providing an algorithm for assessment and an evaluation of current treatment options.
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Howard, J., Telfer, P. (2015). Respiratory and Cardiac Complications. In: Sickle Cell Disease in Clinical Practice. In Clinical Practice. Springer, London. https://doi.org/10.1007/978-1-4471-2473-3_6
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DOI: https://doi.org/10.1007/978-1-4471-2473-3_6
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