Infection and Infection Prophylaxis

  • Jo Howard
  • Paul Telfer
Part of the In Clinical Practice book series (ICP)


Infection is an important cause of morbidity and mortality in SCD. This section covers the majority of common infections encountered in SCD. Infections relating to specific organ systems are also covered in other relevant chapters. Here, we cover invasive pneumococcal disease (IPD) and pneumococcal prophylaxis, as well as other recommended vaccinations and preventive measures when travelling.


Invasive Pneumococcal Disease Pneumococcal Infection Pneumococcal Conjugate Vaccine Pneumococcal Vaccination Oral Penicillin 
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  2. Davies JM, Lewis MPN, Wimperis J, et al. Review of guidelines for the prevention and treatment of infection in patients with an absent or dysfunctional spleen: prepared on behalf of the British Committee for Standards in Hematology by a Working Party of the Hemato-Oncology Task Force. Br J Haematol. 2011;155:308–17.CrossRefPubMedGoogle Scholar
  3. Gaston MH, Verter JI, Woods G, et al. Prophylaxis with oral penicillin in children with sickle cell anemia. A randomized trial. N Engl J Med. 1986;314(25):1593–9.CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag London 2015

Authors and Affiliations

  • Jo Howard
    • 1
  • Paul Telfer
    • 2
  1. 1.Department of HaematologyGuy’s and St Thomas’ HospitalLondonUK
  2. 2.Department of HaematologyRoyal London HospitalLondonUK

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